Results 81 to 90 of about 90,676 (185)

Application of metabolomics in viral pneumonia treatment with traditional Chinese medicine

open access: yesChinese Medicine, 2019
Nowadays, traditional Chinese medicines (TCMs) have been reported to provide reliable therapies for viral pneumonia, but the therapeutic mechanism remains unknown.
Lili Lin   +8 more
doaj   +1 more source

Non-Targeted Metabolomics Reveal Apomorphine’s Therapeutic Effects and Lysophospholipid Alterations in Steatohepatitis

open access: yesAntioxidants
Metabolic dysfunction-associated steatohepatitis (MASH), characterized by progressive inflammation and fibrosis, evolves from metabolic dysfunction-associated steatotic liver disease and significantly heightens the risk of cirrhosis and hepatocellular ...
Hideo Ogiso   +4 more
doaj   +1 more source

A pseudo-targeted HPLC-MS based metabolomics method: effect of bisophenol A on rat metabolome [PDF]

open access: yes, 2012
A pseudo-targeted HPLC-MS based metabolomics method: effect of bisophenol A on rat ...
陈世礼   +4 more
core  

Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

open access: yesJournal of Lipid Research, 2012
Bile acids (BAs) are a group of chemically related steroids recognized as regulatory molecules whose profiles can change in different physio-pathological situations.
Juan C. García-Cañaveras   +3 more
doaj   +1 more source

Leveraging open cheminformatics tools for non-targeted metabolomics analysis of C. elegans: a workflow comparison and application to strains related to xenobiotic metabolism and neurodegeneration [PDF]

open access: yes
Caenorhabditis elegans (C. elegans) is a well-established nematode model for studying metabolism and neurodegenerative disorders, such as Alzheimer’s (AD) and Parkinson’s disease (PD).
Lai, Yunjia   +3 more
core   +1 more source

Metabolomics in Endocrinology: The Way Forward

open access: yesIndian Journal of Endocrinology and Metabolism
Metabolomics is a type of laboratory science used to understand the cellular and metabolic defects in any disease process. It comprehensively identifies endogenous and exogenous low-molecular-weight (
Shinjan Patra, Deep Dutta, Sanjay Kalra
doaj   +1 more source

Evaluating protocols for reproducible targeted metabolomics by NMR

open access: yesThe Analyst
Evaluating how sample preparation methods and data analysis platforms impact measured metabolite concentrations underscores the need for a universal consensus in the followed approaches for metabolomics data analysis.
Darcy Cochran   +6 more
openaire   +3 more sources

Targeted metabolomic approach in men with carotid plaque

open access: yesPLOS ONE, 2018
The aim of the study was to analyse the presence of several metabolites related to atherosclerosis in the plasma of patients with unstable carotid plaque and in the plasma of healthy subjects.We included 20 patients who had undergone carotid endarterectomy and 20 healthy subjects as a control group. All the subjects recruited were male.
Teresa Auguet   +7 more
openaire   +4 more sources

Cellular metabolomics: From sample preparation to high-throughput data analysis

open access: yesJournal of Agriculture and Food Research
Cellular metabolomics, which involves targeted and untargeted analyses of metabolites in in vitro systems, plays a pivotal role in system biology. It offers insights into cell phenotypes and provides a means to monitor cellular activities.
Yang Zhao   +4 more
doaj   +1 more source

Interactive Quality Control and Analysis for Targeted Metabolomics Kits [PDF]

open access: yes, 2019
Open source code will be published soon!Targeted mass spectrometry profiling methods optimized and validated for defined metabolites enable comprehensive routine metabolomics applications.
Yoann Gloaguen (633280)   +6 more
core   +1 more source

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