Results 91 to 100 of about 90,676 (185)

Advancements in Mass Spectrometry-Based Targeted Metabolomics and Lipidomics: Implications for Clinical Research

Molecules
Targeted metabolomics and lipidomics are increasingly utilized in clinical research, providing quantitative and comprehensive assessments of metabolic profiles that underlie physiological and pathological mechanisms.
Nguyen Ky Anh, Nguyen Quang Thu, Nguyen Tran Nam Tien, Nguyen Phuoc Long, Huy Truong Nguyen   +4 more
doaj   +1 more source

Analysis of potential biomarkers for diabetic kidney disease and non-diabetic kidney disease based on urinary metabolomics analysis

BMC Nephrology
Background Diabetic kidney disease (DKD) is a leading cause of chronic renal failure. However, not all patients with type 2 diabetes mellitus (T2DM) develop DKD.
Qiuyue He, Binbin Ye, Huanqin Li, Yuqing Pan, Yan Du, Kai Yang   +5 more
doaj   +1 more source

Targeted and untargeted metabolomics uncovering the effects of Jiawei Ermiao Granule on patients with persistent HPV infection

Frontiers in Cellular and Infection Microbiology
Jiawei Ermiao Granule (JWEMG) is a traditional Chinese herbal formulation widely used in China for the treatment of human papilloma virus (HPV) infections. However, the mechanisms underlying their efficacy in clearing HPV infections remain unclear.
Xiu Li, Xiu Li, Li Ning, Li Ning, Hongting Zhao, Yating Xu, Yating Xu, Yu Si, Yu Si, Jiayi Hua, Qingling Ren, Qingling Ren   +11 more
doaj   +1 more source

Grape and Wine Metabolomics to Develop New Insights Using Untargeted and Targeted Approaches

Fermentation, 2018
Chemical analysis of grape juice and wine has been performed for over 50 years in a targeted manner to determine a limited number of compounds using Gas Chromatography, Mass-Spectrometry (GC-MS) and High Pressure Liquid Chromatography (HPLC).
Farhana R Pinu
doaj   +1 more source

Editorial: Emerging applications of targeted and non-targeted metabolomics to physiology and pathophysiology. [PDF]

Front Physiol
Dowling GM, Aliani M.
europepmc   +3 more sources

Metabolomics Analysis Reveals Characteristic Functional Components in Pigeon Eggs [PDF]

We aimed to identify the characteristic functional components of pigeon eggs and the differences among pigeon, chicken, and quail eggs. We analyzed the metabolite profiles of three kinds of eggs using an untargeted metabolomics-based approach to better ...
Rui Zhang, Shengyong Fu, Qingping Tang, Lingling Chang, Xinyue Shen, Chunyu Mu, Zhu Bu   +6 more
core   +1 more source

Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom. [PDF]

, 2017
The remarkable absence of arachidonic acid (AA) in seed plants prompted us to systematically study the presence of C20 polyunsaturated fatty acids, stearic acid, oleic acid, jasmonic acid (JA), N-acylethanolamines (NAEs) and endocannabinoids (ECs) in 71 ...
Gachet Otanez, Maria Salomé, Gertsch, Jürg, Calarco, Serafina, Boccard, Julien, Schubert, Alexandra   +4 more
core   +1 more source

Integrative Metabolomics of Targeted and Nontargeted Analyses in T2D Progression

Diabetes Care
OBJECTIVE This study aimed to identify metabolites characterizing the progression from normal glucose metabolism (NORM) to prediabetes (PreT2D) and type 2 diabetes (T2D), focusing on stage-specific metabolic shifts (early: NORM to PreT2D; late: PreT2D to T2D) and mechanistic relevance.
Jianhong Ge, Siyu Han, Mengya Shi, Makoto Harada, Shixiang Yu, Jiaqi Zheng, Cornelia Prehn, Jerzy Adamski, Gabi Kastenmüller, Sabrina Schlesinger, Wolfgang Koenig, Birgit Linkohr, Barbara Thorand, Karsten Suhre, Christian Gieger, Annette Peters, Rui Wang-Sattler   +16 more
openaire   +2 more sources

Characterizing poorly controlled type 2 diabetes using 1H-NMR metabolomics [PDF]

Journal Article, Faculty of Natural and Agricultural Sciences, Human Metabolomics-- Potchefstroom Campusntroduction: The prevalence of type 2 diabetes has surged to epidemic proportions and despite treatment administration/adherence, some individuals ...
Ronacher, Katharina, Toit Loots, Du, Van Reenen, Mari, Kleynhans, Léanie, Stander, Zinandré, Theron, Isabella J, Mason, Shayne   +6 more
core   +2 more sources

Metabolomics Insights into Gut Microbiota and Functional Constipation [PDF]

Background: The composition and metabolic activity of the gut microbiota play a crucial role in various health conditions, including the occurrence and development of chronic constipation.
Yu Zhan, Yeong-Yeh Lee, Joo Shun Tan, Uma Mageswary, Mina Ehab Ayad, Daoyuan Xie, Fan Zheng, Yong Yang, Guanting Lu   +8 more
core   +1 more source