Results 111 to 120 of about 90,676 (185)

Rapamycin-encapsulated nanoparticle delivery in polycystic kidney disease mice

Scientific Reports
Rapamycin slows cystogenesis in murine models of polycystic kidney disease (PKD) but failed in clinical trials, potentially due to insufficient drug dosing.
Shinobu Yamaguchi, Randee Sedaka, Chintan Kapadia, Jifeng Huang, Jung-Shan Hsu, Taylor F. Berryhill, Landon Wilson, Stephen Barnes, Caleb Lovelady, Yasin Oduk, Ryan M. Williams, Edgar A. Jaimes, Daniel A. Heller, Takamitsu Saigusa   +13 more
doaj   +1 more source

Smokers with COPD Show a Shift in Energy and Nitrogen Metabolism at Rest and During Exercise

International Journal of COPD, 2020
Olaf Holz,1,* David S DeLuca,2,* Stefan Roepcke,3 Thomas Illig,2 Klaus M Weinberger,4–6 Christian Schudt,7 Jens M Hohlfeld1,2 1Fraunhofer ITEM, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung ...
Holz O, DeLuca DS, Roepcke S, Illig T, Weinberger KM, Schudt C, Hohlfeld JM   +6 more
doaj  

Identification of Salvia miltiorrhiza germplasm resources based on metabolomics and DNA barcoding

Frontiers in Pharmacology
IntroductionSalvia miltiorrhiza radix et rhizoma (Danshen) is a crucial medicinal material for treating cardiovascular and cerebrovascular diseases.
Gaojie He, Jinhui Man, Ying Chen, Xiaoqin Zhang, Xin Wang, Kelu An, Laha Amu, Wenqin Chen, Baowei Wang, Yue Shi, Yue Shi, Xiaohui Wang, Xiaohui Wang, Shengli Wei, Shengli Wei   +14 more
doaj   +1 more source

Using Comparative Metabolomics to Target Cancer

The FASEB Journal, 2015
Because of the complexities and diversity of metabolites, no one analytical approach can cover the whole metabolome. We have been using a range of analytical platforms based around a combination of NMR spectroscopy and mass spectrometry to maximise the coverage of the metabolome and then map these changes onto other datasets such as MRI images ...
openaire   +1 more source

Metabolomics for targeted therapy [PDF]

Nature Reviews Urology, 2012
openaire   +1 more source

MS-based oxylipin targeted metabolomics: applications in clinical research [PDF]

, 2019
Session 6 – CONTRIBUTIONS OF LIPIDOMIC, METABOLOMIC AND FLUXOMIC TO THE KNOWLEDGE IN LIPID PRODUCTION AND NUTRITIONMS-based oxylipin targeted metabolomics: applications in clinical research.
Gladine, Cécile
core  

A búza korai embriófejlődésének mikroanalitikai vizsgálata = Microanalytical investigation of early embryo development in wheat [PDF]

, 2010
Új mikroanalitikai eljárást dolgoztunk ki, beleértve az extrakciót és a származékképzést is, a minimális mennyiségű növényi szerv (egyetlen búza magkezdemény) metabolomjának GC/IT MS módszerrel történő minőségi és mennyiségi meghatározására. Létrehoztunk
Szekeres, András, Barnabás, Beáta, Bartók, Tibor, Varga, Mónika, Jäger, Katalin, Sági, László   +5 more
core  

Targeted Metabolomics Analysen zeigen den Einfluss von Präanalytik und Medikamenteneinnahme auf das humane Metabolom [PDF]

, 2017
The pre-analytical stability of different metabolites in serum and plasma samples of healthy humans was determined. Metabolite concentrations were quantified using targeted metabolomics based on liquid chromatography-tandem mass spectrometry.
Breier, Michaela
core  

Emerging Quantitative Targeted Metabolomics Approaches for Future Inborn Errors of Metabolism Screening. [PDF]

Diagnostics (Basel)
Osman SA, Malki A, Al-Sulaiti H, Al-Dirbashi OY, Elrayess MA.   +4 more
europepmc   +1 more source

Non-targeted metabolomics reveals myocardial metabolic alterations in epileptic rats. [PDF]

PLoS One
Hu Y, Wang Y, Mao Q, Zhu S, Zhang L.
europepmc   +1 more source