Journal of the American College of Emergency Physicians Open, 2022 Objectives The objective of this study was to evaluate the performance of non‐targeted hepatitis C virus (HCV) screening in emergency departments (EDs) and other healthcare settings in terms of patients identified with HCV infection and linked to HCV ...
Cody A. Chastain +13 more
doaj +1 more source
Journal of Xenobiotics, 2021 The recent advances of novel methodologies such as non-targeted and suspect screening based on high-resolution mass spectrometry (HRMS) have paved the way to a new paradigm for exposure assessment.
Juliana Monteiro Bastos da Silva +5 more
doaj +1 more source
The association between socio-demographic characteristics and adherence to breast and colorectal cancer screening: Analysis of large sub populations [PDF]
, 2011 Background Populations having lower socioeconomic status, as well as ethnic minorities, have demonstrated lower utilization of preventive screening, including tests for early detection of breast and colorectal cancer.
Rachel Wilf-Miron +6 more
core +1 more source
Sample preparation techniques for suspect and non-target screening of emerging contaminants [PDF]
Chemosphere, 2022 The progress in sensitivity and resolution in mass spectrometers in recent years provides the possibility to detect a broad range of organic compounds in a single procedure. For this reason, suspect and non-target screening techniques are gaining attention since they enable the detection of hundreds of known and unknown emerging contaminants in various
Parvaneh Hajeb +3 more
openaire +2 more sources
Evaluation of Phage Display Discovered Peptides as Ligands for Prostate-Specific Membrane Antigen (PSMA) [PDF]
, 2013 The aim of this study was to identify potential ligands of PSMA suitable for further development as novel PSMA-targeted peptides using phage display technology. The human PSMA protein was immobilized as a target followed by incubation with a 15-mer phage
A Ghosh +48 more
core +7 more sources
EPMA position paper in cancer:current overview and future perspectives [PDF]
, 2015 At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive, and personalized medicine (PPPM). Individual patients will participate in more aspects of their healthcare.
Bubnov, Rostylav +7 more
core +5 more sources
Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]
, 2018 Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R. +3 more
core +2 more sources
Patient-centric trials for therapeutic development in precision oncology [PDF]
, 2015 An enhanced understanding of the molecular pathology of disease gained from genomic studies is facilitating the development of treatments that target discrete molecular subclasses of tumours.
A Hollebecque +60 more
core +1 more source
Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]
, 2009 Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core +2 more sources
Suspect screening of maternal serum to identify new environmental chemical biomonitoring targets using liquid chromatography-quadrupole time-of-flight mass spectrometry. [PDF]
, 2017 The use and advantages of high-resolution mass spectrometry (MS) as a discovery tool for environmental chemical monitoring has been demonstrated for environmental samples but not for biological samples.
Friesen, Matthew M +5 more
core +1 more source