Results 161 to 170 of about 1,449,640 (302)

Development of simulation scenarios for surgeons' non-technical skills evaluation. [PDF]

Global Surg Educ
Anton NE, Anderson-Montoya B, Holmstrom A, Obuseh M, Yan Y, Miller PM, Li WS, AbuHasan Q, Yu D, Stefanidis D.   +9 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Effectiveness of non-technical skills training for healthcare professionals in emergency departments: a systematic review. [PDF]

Scand J Trauma Resusc Emerg Med
Zhang Y, Wang Y, Jiang M, Sun X, Tang L.
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

User evaluation of a virtual reality simulation for anaesthesiologists-intensivists for non-technical skills. [PDF]

PEC Innov
Hoek K, van Velzen M, Sarton E, Jaschinski C.   +3 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A European survey on non-technical skills in robotic thoracic surgery for lung resections. [PDF]

Interdiscip Cardiovasc Thorac Surg
Shahin GMM, Verhagen MJ, Hutteman M, Wink J, Stamenkovic SA, Durand M, Baste JM, Melfi F, Braun J.   +8 more
europepmc   +1 more source

Non-technical skills and teamwork in trauma: from the emergency department to the operating room. [PDF]

Front Med (Lausanne), 2023
Alexandrino H, Martinho B, Ferreira L, Baptista S.   +3 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

AI-Based Assessment of Non-Technical Skills in Prehospital Simulations: A Comparative Validation Study. [PDF]

Healthcare (Basel)
Mitsuhashi M, Akiba Y, Saitou M, Suzuki K, Ogawa S, Masuno T.   +5 more
europepmc   +1 more source