Results 171 to 180 of about 1,449,640 (302)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Beyond non-technical skills: training ophthalmologists to appraise and integrate emerging technologies. [PDF]

Eye (Lond)
Whitelaw TA, Fioratou E.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Feasibility of large language models for assessing and coaching surgeons' non-technical skills. [PDF]

Npj Health Syst
Obuseh M, Singh S, Anton NE, Gardiner R, Stefanidis D, Yu D.   +5 more
europepmc   +1 more source

Importance of non-technical skills: SACRED in advanced endoscopy. [PDF]

Frontline Gastroenterol, 2023
Shiha MG, Ravindran S, Thomas-Gibson S, Sanders DS, Ching HL.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The role of leadership in enhancing non-technical skills in healthcare: a qualitative study in a Balkan context. [PDF]

Hum Resour Health
Hodza-Beganovic R, Berggren P, Edelbring S.   +2 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Simulation-Based Curriculum for Medical Undergraduates in Non-technical Skills. [PDF]

Cureus
Kaur M, Ramachandran R, Nagarajappa A, Goswami D, Muthiah T, Yalla B, Roy A.   +6 more
europepmc   +1 more source

The need for non-technical skills education in orthopedic surgery. [PDF]

BMC Med Educ, 2023
Alzahrani KH, Abutalib RA, Elsheikh AM, Alzahrani LK, Khoshhal KI.   +4 more
europepmc   +1 more source