Results 131 to 140 of about 478,729 (278)

Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang   +10 more
wiley   +1 more source

Acoustic Branding, Non-Traditional Trademarks and the Graphical Representation Requirement: A Conceptual and Empirical Analysis

open access: yes, 2019
Considers the growing range of sound-based stimuli found in multisensory marketing and branding in Hong Kong and Singapore, whether the criteria formulated in Shield Mark BV v Kist (t/a Memex) (C-283/01) (ECJ) for establishing the registrability of acoustic trade marks are now insufficient, and whether the two jurisdictions should introduce a more ...
Lim, Eugene C, Samtani, Anil
openaire   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Environmental Labeling, Protected Geographical Indications and the Interests of Developing Countries [PDF]

open access: yes
Among developing countries, one can identify both proponents and opponents of extending the use of geographical indications (GIs) beyond wines and spirits.
Grote, Ulrike
core   +1 more source

B4GALNT4‐Mediated Glycosylation of PDK1 Activates the PI3K‐AKT Signaling Pathway to Promote Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies B4GALNT4 as a key driver of prostate cancer (PCa). It shows that B4GALNT4 glycosylates PDK1 protein at the N531 site, which stabilizes the PDK1 and constitutively activates the PI3K‐AKT pathway. This mechanism promotes tumor cell proliferation, migration, and invasion. The findings establish the B4GALNT4‐PDK1 glycosylation axis as
Shaoqin Jiang   +12 more
wiley   +1 more source

Medication adherence rates in patients with ocular inflammatory disease. [PDF]

open access: yesFront Med (Lausanne)
Chew ZRJ   +5 more
europepmc   +1 more source

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