Epithelial immune activation and intracellular invasion by non-typeable Haemophilus influenzae [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 Type-2 low asthma affects 30-50% of people with severe asthma and includes a phenotype characterized by sputum neutrophilia and resistance to corticosteroids. Airways inflammation in type-2 low asthma or COPD is potentially driven by persistent bacterial
Mary A. Brown +6 more
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The DmsABC Sulfoxide Reductase Supports Virulence in Non-typeable Haemophilus influenzae [PDF]
Frontiers in Microbiology, 2021 Although molybdenum-containing enzymes are well-established as having a key role in bacterial respiration, it is increasingly recognized that some may also support bacterial virulence.
Rabeb Dhouib +8 more
doaj +7 more sources
Can non‐typeable Haemophilus influenzae carriage surveillance data infer antimicrobial resistance associated with otitis media? [PDF]
Pediatric Investigation, 2023 Importance In remote communities of the Northern Territory, Australia, children experience high rates of otitis media (OM), commonly caused by non‐typeable Haemophilus influenzae (NTHi).
Sophia Bowman‐Derrick +12 more
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Multi-Component Vaccine Candidates Against Non-Typeable Haemophilus influenzae [PDF]
VaccinesBackground: Haemophilus influenzae (Hi), a Gram-negative bacterium, is divided into two broad categories: encapsulated and non-capsulated isolates, also called non-typeable Hi isolates (NTHi).
Nouria Belkacem +2 more
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Characterization of a conserved outer-membrane protein in non-typeable Haemophilus influenzae with an unidentified impact on phenotype [PDF]
Microbiology SpectrumNon-typeable Haemophilus influenzae (NTHi) is an opportunistic bacterial pathogen of the human airway and is a cause of significant morbidity and mortality worldwide.
Ashley J. Fraser +5 more
doaj +2 more sources
A rare case of invasive non-typeable Haemophilus influenzae spondylodiscitis and periprosthetic joint infection [PDF]
Journal of Bone and Joint Infection, 2021 A non-typeable Haemophilus influenzae (NTHi) was responsible for an invasive infection including bacteremia, spondylodiscitis with epidural abscess, and periprosthetic hip infection in a 79-year-old woman, triggered by a superinfected ethmo-orbital ...
K. Sermet +9 more
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Non-typeable Haemophilus influenzae airways infection: the next treatable trait in asthma? [PDF]
European Respiratory Review, 2022 Asthma is a complex, heterogeneous condition that affects over 350 million people globally. It is characterised by bronchial hyperreactivity and airways inflammation.
Mary Ashley Brown +3 more
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Non-typeable Haemophilus influenzae and purpura fulminans. [PDF]
BMJ Case Rep, 2020 Haemophilus influenzae typically causes illness and infection in the paediatric population. We report a case of a 53-year-old man who developed invasive non-typeable H. influenzae infection associated with purpura fulminans and multiorgan failure.
Beechar VB, de la Flor C, Medford RJ.
europepmc +3 more sources
The evidence for non-typeable Haemophilus influenzae as a causative agent of childhood pneumonia [PDF]
Pneumonia, 2017 Haemophilus influenzae type b (Hib) was a major cause of bacterial pneumonia in children prior to the introduction of Hib-conjugate vaccines. The widespread use of Hib-conjugate vaccines has resulted in a significant decline in the number of cases of ...
Mary P E Slack
doaj +4 more sources
Chorioamnionitis and early pregnancy loss caused by ampicillin-resistant non-typeable Haemophilus influenzae [PDF]
IDCases, 2023 Haemophilus influenzae can cause intra-amniotic infection and early pregnancy loss. The mode of transmission and risk factors for H. influenzae uterine cavity infections are unknown.
Yuji Nishihara +14 more
doaj +2 more sources