Results 51 to 60 of about 11,363,734 (290)
Paper deals with the non-uniform covering method that is aimed at deterministic global optimization. This method finds a feasible solution to the optimization problem numerically and proves that the obtained solution differs from the optimal by no more ...
Evtushenko Yury, Posypkin Mikhail
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Pseudo-planar deformations of a linearized elastic solid
The equations of motion for the pseudo-planar motions of a classical linearized elastic solid and an incompressible linearized elastic solid undergoing non-uniform rotation about a vertical axis are derived. The pseudo-planar motions for both a classical
E. Momoniat, C. Harley
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Analytical Solution for Bichromatic Waves on Linearly Varying Currents
It is well-known that the bound long waves play an important role on beach morphology. The existence of the current will modify the intensity of the waves.
Mu-Jung Lee, Shih-Chun Hsiao
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Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
A non-uniform Datko–Pazy theorem for bounded operator semigroups
We present a non-uniform analogue of the classical Datko-Pazy theorem. Our main result shows that an integrability condition imposed on orbits originating in a fractional domain of the generator (as opposed to all orbits) implies polynomial stability of a bounded $C_0$-semigroup.
Paunonen, Lassi +2 more
openaire +4 more sources
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Pairing, waltzing and scattering of chemotactic active colloids
We study theoretically an active colloid whose polar axis of self-propulsion rotates to point parallel (antiparallel) to an imposed chemical gradient. We show that the coupling of this ‘chemotactic’ (‘antichemotactic’) response to phoretic translational ...
Suropriya Saha +2 more
doaj +1 more source
Corrosion models of a mounded horizontal pressure vessel in a probabilistic approach [PDF]
The computations of fuel tanks are bound to cover uncertainties related to geometric and material imperfections, post-welding stresses, non-uniform settlement, and shell degradation due to corrosion.
Mateusz Sondej +2 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

