Results 101 to 110 of about 431,042 (280)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

On the existence of a priori bounds for positive solutions of elliptic problems, I

Revista Integración, 2019
This paper gives a survey over the existence of uniform L∞ a priori bounds for positive solutions of subcritical elliptic equations (P)p     -\Delta_p u =f(u),  in  \Omega,    u = 0, on \partial\Omega widening the known ranges of subcritical ...
Rosa Pardo
doaj  

Numerical method for second order singularly perturbed delay differential equations with fractional order in time via fitted computational method

Partial Differential Equations in Applied Mathematics
The numerical solution of time fractional parabolic differential equations with singular perturbations and delay is the subject of this article.
Nuru Ahmed Endrie, Gemechis File Duressa
doaj   +1 more source

Non-uniform Bound on Normal Approximation of Latin Hypercube Sampling

Journal of Mathematics Research, 2009
Loh (Loh, W.L, 1996b) established a Berry-Esseen type bound for $W$, the random variable based on a latin hypercube sampling, to the standard normal distribution. He used an inductive approach of Stein's method to give the rate of convergence $\frac{C_d}{\sqrt{n}}$ without the value of $C_d.$ In this article, we use a concentration inequality approach ...
Kritsana Neammanee, Petcharat Rattanawong   +1 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

α-Mean curvature flow of non-compact complete convex hypersurfaces and the evolution of level sets

Advances in Nonlinear Analysis
We consider the α\alpha -mean curvature flow for convex graphs in Euclidean space. Given a smooth, complete, strictly convex, non-compact initial hypersurface over a strictly convex projected domain, we derive uniform curvature bounds, which are ...
Kang Hyunsuk, Lee Ki-Ahm, Lee Taehun
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Numerical solution for laminar unsteady flow about fixed and oscillating cylinders

Computer Assisted Methods in Engineering and Science, 2023
This paper presents a finite-difference solution of the two-dimensional, time dependent incompressible Navier-Stokes equations for laminar flow about fixed and oscillating cylinders placed in an otherwise uniform flow. Using boundary fitted coordinates,
László Baranyi, Masataka Shirakashi
doaj