Results 81 to 90 of about 17,865,208 (292)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

The Study of Thawing Characteristics and Mechanism of Frozen Beef in High Voltage Electric Field

open access: yesIEEE Access, 2020
The aim is to comprehensively and further explore the thawing characteristics and mechanism of frozen beef in high voltage electric field (HVEF). In this paper, the frozen beef was thawed under blocking ionic wind and changing voltage, electrode distance
Yaming Zhang, Changjiang Ding
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Decomposition of Acoustic and Entropy Modes in a Non-Isothermal Gas Affected by a Mass Force

open access: yesArchives of Acoustics, 2018
Diagnostics and decomposition of atmospheric disturbances in a planar flow are considered in this work. The study examines a situation in which the stationary equilibrium temperature of a gas may depend on the vertical coordinate due to external forces ...
Sergey LEBLE, Anna PERELOMOVA
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

FEM analysis of electric field distribution for polymeric insulator under different configuration of non-uniform pollution

open access: yes, 2021
Considering the extensive use of high voltage insulators, the reliable performance of insulators is challenged by various weather conditions such as pollution.
Moradi CheshmehBeigi, H   +9 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Cluster-driven non-uniform characteristic analysis of underwater target acoustic scattering field

open access: yesFrontiers in Physics
Underwater small targets typically exhibit non-centrosymmetric geometries, resulting in a highly spatially inhomogeneous acoustic scattering field under active sonar detection.
Tianyang Xu, Hongjian Jia, Jixing Qin
doaj   +1 more source

Alfvén wave propagation and mode coupling in non-uniform media [PDF]

open access: yes
In this thesis we investigate the process of MHD Alfvén-fast wave mode coupling in non-uniform media. To do this we begin by developing a Cartesian model using the linear MHD equations.
Davies, Rachel
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

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