Results 81 to 90 of about 17,181,475 (289)
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Numerical analysis of quantum-mechanical non-uniform E x B drift: Non-uniform electric field [PDF]
, 2016 We have numerically solved the two-dimensional time-dependent Schrodinger equation for a charged particle in the presence of a non-uniform electric field E = E (1-y/L-E) e(y) as well as a non-uniform magnetic field B = B (1-y/L-B) e(z).
Chan, Poh Kam +2 more
core +1 more source
A generalisation to cohesive cracks evolution under effects of non-uniform stress field
Vietnam Journal of Mechanics, 2018 The aim of the present work is to study the stabilizing effect of the non-uniformity of the stress field on the cohesive cracks evolution in two-dimensional elastic structures.
Tuan-Hiep Pham +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Analogues of Non-Gibbsianness in Joint Measures of Disordered Mean Field Models [PDF]
, 2002 It is known that the joint measures on the product of spin-space and disorder space are very often non-Gibbsian measures, for lattice systems with quenched disorder, at low temperature.
Külske, Christof, Külske, Christof,
core +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Multiscale enhanced non‐uniform transformation field analysis
International Journal for Numerical Methods in EngineeringAbstractEnhanced transformation field analysis (E‐TFA), recently proposed for reduced‐order modeling, is here formulated for and applied to multiscale analysis. The approach is able to reproduce a highly complex nonlinear macroscale behavior, resulting from a microstructure with cohesive interfaces embedded in an elasto‐plastic bulk.
A. Mishra +4 more
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source