Results 91 to 100 of about 187,835 (306)

Teaching Peace – The Need for Teacher Training in Poland to Promote Peace [PDF]

open access: yes, 2015
The aim of the paper is to stimulate the discussion on peace education and the need of teacher training for peace and multicultural understanding. This paper is organized in two sections: the first section presents the importance of peace education for ...
Leek, Joanna
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Hindu Buddha according to the theology of the Bengali Vaishnava Acharya Bhaktivedanta Swami [PDF]

open access: yes, 1998
In the broad Indian religious culture we find two basic concepts of the inner structure of the Holy. The Advaita religion believes in the 'not-two' will say absolute 'oneness' of the ultimate reality.
Weber, Edmund
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Latin American Christology: A God Who Liberates

open access: yesReligions
This paper will investigate the dynamic nature of Latin American Christology, a Christology that cannot be separated from the tenets of liberation theology.
Amanda Rachel Bolaños
doaj   +1 more source

On the Mechanisms of Moral Development in Evolutionary Historical Psychology [PDF]

open access: yesPsychology in Russia: State of Art, 2009
Rough calculations demonstrate that while demographic densities and the technical capacity for mutual destruction have increased throughout the millennia, the violent death rate – the average number of deliberate killings per capita per time unit – has ...
Akop P. Nazaretyan
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Corruption, non-violence et résilience

open access: yesJournal of Ethics in Higher Education
La corruption s’insinue dans les structures sociales non pas comme un acte isolé, mais comme une atmosphère diffuse qui altère progressivement les repères éthiques et moraux.
Jimmy Mpezo
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Manufactured vulnerability: eco-activist tactics in Britain [PDF]

open access: yes, 1999
This article examines the development of tactics in radical environmentalist protests against new roads and other environmental issues in Britain during the 1990s. These tactics depend heavily upon the technical creativity of protesters. Their repertoire
Doherty, BJA
core   +1 more source

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