Results 81 to 90 of about 23,393,866 (298)

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Decolonising non-violence: what Indigenous wisdom traditions contribute to non-violence teacher education

open access: yesInternational Journal of Development Education and Global Learning, 2023
Knowledge systems and social philosophies from Indigenous communities in the Global South have long promoted non-violence through a sense of shared humanity and community building, and as such are valid counter-hegemonic alternatives to the existing ...
doaj   +2 more sources

Domestic Abuse: Instrumental Violence and Economics Incentives [PDF]

open access: yes
A large fraction of domestically abused women report that their partners interfere with their participation in education and employment. As of yet, mainstream economics has not dealt in any systematic way with this phenomenon and its implications for ...
Dan Anderberg, Helmut Rainer
core  

Health and the primary prevention of violence against women [PDF]

open access: yes, 2014
This position paper focuses on the primary prevention of violence perpetrated by men against women. It develops a position on primary prevention (as distinct from secondary and tertiary interventions).

core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Man-object, Interpersonal and Man-machine Relationships — An Ethical Perspective on Artificial Intelligence

open access: yesContemporary Social Sciences, 2019
Traditional social ethics has always been centered on human relationships. In recent years, modern ethics began to systematically reflect the relationships between humans and objects, and the future ethics will need to account for the relationships ...
He Huaihong, Zhuang Qiuyue
doaj   +1 more source

Prison violence and the mission statement [PDF]

open access: yes, 1994
A report prepared by the Prison Violence Project, Kingston, Ontario, April 16, 1994. Rudolf Martens, Chairperson; J. Campbell, Research Director. Discusses the achievements and failures of the prison system after the adoption of a "mission statement" in ...
Prison Violence Project
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The Violence of Non-Violence: A Systematic Mixed-Studies Review on the Health Effects of Sanctions. [PDF]

open access: yesInt J Soc Determinants Health Health Serv, 2023
Chaufan C, Yousefi N, Zaman I.
europepmc   +1 more source

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