Results 91 to 100 of about 2,708,318 (331)

What Difference Do Alternative Immigration and Integration Levels Make to Western Europe? [PDF]

open access: yes, 1992
The population of Western Europe (EC plus EFTA) is seen as consisting of three subpopulations: the natives, the East-European immigrants, and the non-European immigrants.
Lutz, W., Prinz, C.
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Palbociclib in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer: A Systematic Scoping Review of Real-World Evidence from Countries Outside of Western Regions that Are Underrepresented in Clinical Trials

open access: yesOncology and Therapy
Introduction Limited awareness exists regarding real-world data (RWD) for palbociclib in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced/metastatic breast cancer in populations from certain countries ...
Amit Rauthan   +3 more
doaj   +1 more source

Perspective Paper – Cultural and Religious Heritage of Servant Leadership in India [PDF]

open access: yesColombo Business Journal
Servant Leadership is a contemporary philosophy of leadership suggesting that the most effective leaders serve those around them. It is a philosophy emphasising the prioritisation of serving others over oneself and is particularly aligned with non ...
Dipanwita Biswas   +2 more
doaj   +1 more source

Against Critical Race Theory [PDF]

open access: yes, 2017
Critical Race Theory (CRT) seeks to apply the negative dialectics of critical theory to the intersection of race, law, and power in the pursuit of racial and ethnic equality in Western society.
Mocombe, Paul C.
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Orientalisme Romantis: Imajinasi Tentang Timur Sebelum Edward Said

open access: yesJurnal Studi Al-Quran, 2015
Orientalism is a 1978 book by Edward W. Said, in which Said studies the cultural representations that are the bases of Orientalism, the West's patronizing perceptions and fictional depictions of "The East" — the societies and peoples who inhabit the ...
Gumillar Irfanullah
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Institutional matrices theory as a framework for both western and non-western people to understand the global village” [PDF]

open access: yes
Neither criticising Western social theory nor constructing an alternative kind of social theory is currently being thought of as a creative and fruitful method for social theorizing around the world today.
Kirdina, Svetlana, Sandstrom, Gregory
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy