Results 111 to 120 of about 943,588 (293)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Boda-bodas Rule: Non-agricultural Activities and Their Inequality Implications in Western Kenya [PDF]
Engagement in non-agricultural activities in rural areas can be classified into survival-led or opportunity-led. Survival-led diversification would decrease inequality by increasing the incomes of poorer households and thus reduce poverty.
Toman Omar Mahmoud +2 more
core +2 more sources
African Christian TheologyDescribing the shift of World Christianity from the Global North to the Global South, Mark Noll posited that “as much as the new shape of Christianity in the world affects general world history, much more does it influence matters of Christian belief ...
Joshua Robert BARRON, Martin MUNYAO
doaj +1 more source
Collegiate Singers, March 28, 1993
, 2016 Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, March 28, 1993, 3:00 p.m., the 410th concert of the School of Music’s 1992-1993 season.Collegiate Singers, Stephen Zegree, conductor ...
Collegiate Singers (Western Michigan University)
core
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Status of Energy Efficiency in the Western Balkans : A Stocktaking Report
, 2010 Across the Western Balkan region, countries exhibit relatively high levels of energy intensity, a high energy savings potential among energy end-users, and heavy dependence on imported hydrocarbons ...
World Bank
core +2 more sources
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Rethinking Approaches to Negotiation Training in Russia and other Countries
Евразийская интеграция: экономика, право, политикаThe article is devoted to the problems of negotiation training and research of modern negotiation practices in Russia and abroad in the context of expanding traditional diplomatic tools through the active involvement of non-state actors in world ...
N. V. Shevchuk
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source