Results 121 to 130 of about 2,695,761 (299)
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Rethinking Approaches to Negotiation Training in Russia and other Countries
The article is devoted to the problems of negotiation training and research of modern negotiation practices in Russia and abroad in the context of expanding traditional diplomatic tools through the active involvement of non-state actors in world ...
N. V. Shevchuk
doaj +1 more source
The EU's Role in Supporting Crisis-Hit Countries in Central and Eastern Europe [PDF]
The crisis has hit central and eastern European countries harder than other regions of the world. In this policy contribution Resident Scholar Zsolt Darvas looks at the role of the EU and its institutions in supporting crisis-hit CEE countries; the ...
Zsolt Darvas
core +1 more source
The ethno-wiki project: ethnographic museums in Wikimedia commons [PDF]
The ethno-wiki project is an initiative to use Wikimedia as a tool to save vulnerable heritage collections of non-western cultures and revive the research on ethnographic artefacts.
van der Zee, Paulina
core +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Special editor's column : Performance literature and the written word : Lost in transcription? [PDF]
This volume examines performance and the phenomenon of performance literature in a highly comparative framework. Literatures around the world, both in the past and in contemporary times, were and are experienced through live performance.
Thomas, Rosalind
core
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
A Determination of the Trade Creation and Diversion Effects of Regional Trade Agreements in the Western Hemisphere [PDF]
With the recent proliferation of Regional Trade Agreements (RTAs) the tendency world-wide has been seemingly toward trade liberalization. This thesis is primarily concerned with the impacts RTAs have had in the Western Hemisphere regarding agricultural ...
Dufour, Elizabeth Anne +2 more
core +1 more source

