Results 41 to 50 of about 17,236,912 (253)

Social sequencing to determine patterns in health and work-family trajectories for U.S. women, 1968–2013

open access: yesSSM: Population Health, 2018
Background: Women’s social roles (partnership, parenthood, and worker status) are associated with health, with more roles being associated with lower mortality rates. Few studies have examined social roles using a lifecourse perspective to understand how
Sarah McKetta   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Building Better Lives for Working Poor Women [PDF]

open access: yes, 2011
Women are heavily overrepresented in low-value and unstable work. Their unpaid and largely unrecognised caring work within the household greatly limits their choice of employment. This ‘time poverty’, as well as lack of mobility, limits women&
English, Rachel   +2 more
core  

Impact of Indian Demonetization on Working and Non-Working Married Women: An Interpretative Phenomenological Analysis [PDF]

open access: yes, 2020
The sudden announcement of demonetization in India caused an immediate financial crisis that cascaded throughout the whole country and consequently caused suffering in the lives of many people, one such group being married women.
Dar, Imtiyaz A.   +5 more
core   +1 more source

Women, occupation, marital status and non-communicable disease risk factors: findings from the Tehran Lipid and Glucose Study

open access: yesPayesh, 2008
Objective(s): To investigate the relationship between the presence of risk factors for non-communicable diseases and occupation and marital status in Tehran women.
Azizi F, Ainy E
doaj  

Epidemiology of dysmenorrhea among workers in Upper Egypt; A cross sectional study

open access: yesMiddle East Fertility Society Journal, 2018
Objective: To investigate the epidemiology of dysmenorrhea amongst women in two textile factories in Beni-Suef, Egypt compared to non-working controls. Study design: A cross sectional study. Setting: Beni-Suef, Egypt. Materials and methods: The study was
Ahmed E. Arafa   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Prevalence of Piriformis Syndrome in Working and Non Working Women with Low Back Pain

open access: yesJournal Riphah College of Rehabilitation Sciences, 2014
Background: Piriformis muscle syndrome is often over looked in the clinical practice as its presentation resembles with other pathology (back, buttock, and leg).
Syed Imtiaz Hussain Shah   +2 more
doaj  

Home - About - Disclaimer - Privacy