Results 91 to 100 of about 1,274,147 (339)

Non-parametric surrogate model method based on machine learning with application on low-pressure steam turbine exhaust system [PDF]

, 2022
Jiajun Cao, Qingbiao Li, XU Li-ping, Rui Yang, Yuejin Dai   +4 more
openalex   +1 more source

The Relative Efficiency of Active Labour Market Policies: Evidence from a Social Experiment and Non-Parametric Methods [PDF]

We re-analyze the effects of a Danish active labour market program social experiment that included a range of sub-treatments, including monitoring, job search assistance and training.
Rosholm, Michael, Svarer, Michael, Vikström, Johan   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Non-parametric load extrapolation based on load extension for semi-axle of wheel loader

Advances in Mechanical Engineering, 2017
Load extrapolation is the paramount step in compiling load spectra of the mechanical components. To avoid the limitation of the stationary processes in parametric extrapolation methods, the non-parametric extrapolation method is widely investigated in ...
Jixin Wang, Yan Li, Zhujin Jiang
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Outcome risk model development for heterogeneity of treatment effect analyses: a comparison of non-parametric machine learning methods and semi-parametric statistical methods

BMC Medical Research Methodology
Background In randomized clinical trials, treatment effects may vary, and this possibility is referred to as heterogeneity of treatment effect (HTE).
Edward Xu, Joseph Vanghelof, Yiyang Wang, Anisha Patel, Jacob Furst, Daniela Stan Raicu, Johannes Tobias Neumann, Rory Wolfe, Caroline X. Gao, John J. McNeil, Raj C. Shah, Roselyne Tchoua   +11 more
doaj   +1 more source

SVM approach for non-parametric method in classification and regression learning process on feature selection with $epsilon$-insensitive region [PDF]

, 2019
M. Premalatha, C. Vijayalakshmi, C. Vijayalakshmi   +2 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Non-Parametric Methods for Detection of Adulteration of Concentrated Orange Juice for Manufacturing [PDF]

, 1978
Thomas F. Schatzki, Carl E. Vandercook
openalex   +1 more source