Results 121 to 130 of about 36,520 (265)

New perspectives on VEGF signalling in Alzheimer's disease

Brain Pathology, EarlyView.
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery, Seth Love, J. Scott Miners   +2 more
wiley   +1 more source

Multiclass Diabetic Retinopathy Classification based on Low-Rank Adaptation

CLEI Electronic Journal
Diabetic retinopathy is a vision impairment associated with diabetes mellitus, a common medical condition. Retinographic imaging analysis of retinal fundus images is the predominant method of diagnosing this eye complication.
Sebastián Ferreria-Caballero, Diego P. Pinto-Roa, José Luis Vázquez Noguera, Jordan Ayala, Pastor Pérez-Estigarribia, Pedro E. Gardel-Sotomayor   +5 more
doaj   +1 more source

Incidence, Progression and Determinants of Diabetic Retinopathy in Type 2 Diabetes in Australasia: A Systematic Review and Meta‐Analysis

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Current evidence on incidence and progression rate of diabetic retinopathy reveals disparities across Australasia, and no pooled estimates are available to guide region‐wide planning. This review and meta‐analysis assesses the overall incidence, determinants and progression of diabetic retinopathy in Australasia.
Getasew Alemu Mersha, Mesert Derbew Molla, Ranjay Chakraborty, Georgia Kaidonis, Stewart Lake, Jamie Craig, José Estevez   +6 more
wiley   +1 more source

Cataract and diabetic retinopathy

Community Eye Health Journal, 2011
When managing the cataract of a patient with diabetes, you should remember that cataract surgery may make diabetic retinopathy worse. Eyes with mild to moderate non-proliferative diabetic retinopathy at the time of surgery are considered less at risk ...
James Rice
doaj  

Diabetic Retinopathy –Incidence And Risk Factors In A Community Setting- A Longitudinal Study

Scandinavian Journal of Primary Health Care, 2018
Aim: To evaluate the natural history of diabetic retinopathy (DR) in diabetic patients and to assess long term risk for other chronic diseases associated with DR. Methods: Retrospective, community-based study.
Michal Shani, Tali Eviatar, Doron Komaneshter, Shlomo Vinker   +3 more
doaj   +1 more source

Comprehensive Assessment of the KDM2B‐Associated Neurodevelopmental Disorder and the 12q24.31 Microdeletion Syndrome

Clinical Genetics, EarlyView.
We set out to characterize genotype–phenotype correlations in the recently delineated KDM2B‐associated neurodevelopmental disorder. We observe a highly penetrant CxxC domain‐related phenotype with distinct facial features supported by GestaltMatcher. In contrast, our findings point to variable expressivity and incomplete penetrance of loss‐of‐function ...
Amber S. E. van Oirsouw, Tzung‐Chien Hsieh, Martijn Koetsier, Abdulrazak Alali, Fatimah Albuainain, Elena Bacchelli, Tahsin Stefan Barakat, Yline Capri, Sandra Chantot‐Bastaraud, Valeria Capra, Deanna Alexis Carere, Emma Clement, Nour Elkhateeb, Madeleine Franchi, Jing‐Mei Li, Nicole Matthews, Vanda McNiven, Sarju G. Mehta, Masayuki Nakamura, Chanika Phornphutkul, Nicole Revencu, Marcello Scala, Natalie Shallow, Jennifer Stefanich, Marta Viggiano, Paola Visconti, Susan Walker, Federico Zara, Mariëlle Alders, Bobby P. C. Koeleman, Renske Oegema   +30 more
wiley   +1 more source

Evaluation of Correlation between Severity of Dry Eye Syndrome and Retinopathy in Patients with Diabetes Mellitus

Armaghane Danesh Bimonthly Journal, 2007
: Introduction & Objective: Diabetes is one of the most common systemic diseases. Dry eye syndrome is one of the eye involvements in diabetic patient. Evaluation of correlation between dry eye syndrome and diabetic retinopathy in patients with insipidus
AR Foroutan, A ASghari, N Afsar, A Vadipour, M Joushghani, N Nilforoushan, AA Nikeghbali, M Mirsamadi   +7 more
doaj  

Diabetes Alters Diurnal Rhythm of Electroretinogram in db/db Mice [PDF]

, 2019
Diabetic retinopathy (DR) is the most common complications of diabetes and a leading cause of blindness in the United States. The retinal neuronal changes precede the vascular dysfunction observed in DR.
Bhatwadekara, Ashay D., Di, Rong, Luo, Qianyi, Mathew, Deepa   +3 more
core  

Zoom-in-Net: Deep Mining Lesions for Diabetic Retinopathy Detection

, 2017
We propose a convolution neural network based algorithm for simultaneously diagnosing diabetic retinopathy and highlighting suspicious regions. Our contributions are two folds: 1) a network termed Zoom-in-Net which mimics the zoom-in process of a ...
A Jamaludin, BJ Frey, CI Sànchez, E Decencière, L Tang, MD Abràmoff, MD Abràmoff, O Russakovsky, R Pires, V Gulshan   +9 more
core   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source