Results 181 to 190 of about 98,461 (251)

Multiparametric Quantitative Ultrasound as a Potential Imaging Biomarker for Noninvasive Detection of Nonalcoholic Steatohepatitis: A Clinical Feasibility Study. [PDF]

Diagnostics (Basel)
Chattopadhyay T, Chan HJ, Le DC, Wang CY, Tai DI, Zhou Z, Tsui PH.   +6 more
europepmc   +1 more source

Protein Kinase C Family: Structures, Biological Functions, Diseases, and Pharmaceutical Interventions

MedComm, Volume 6, Issue 11, November 2025.
Ligand–receptor binding activates PLC, which hydrolyzes the membrane lipid PIP2, generating the second messenger's IP3 and DAG. IP3 binding to ER receptors causes Ca2⁺ release. Subsequently, PKC are recruited to the membrane, which induces a conformational change in PKC, leading to the full enzymatic activation.
Yongqi Li, Yuhan Jiang, Zhengxi Hu, Shenglan Yang, Longyin Li, Chaohu Xiong, Ya Gao, Weiguang Sun, Yonghui Zhang   +8 more
wiley   +1 more source

Macrophage inhibition in the alleviation of nonalcoholic steatohepatitis caused by bariatric surgery. [PDF]

Genes Immun
Zheng Q, Deng S, Chen X, Wang Y, Yang Y.
europepmc   +1 more source

Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences

Molecular Nutrition &Food Research, Volume 69, Issue 21, November 2025.
This retrospective study evaluated the effects of nutraceutical supplementation (NS) and a Mediterranean hypocaloric diet (MHD) in NAFLD patients. Forty‐five overweight/obese subjects followed MHD with or without NS. After 3 months, only the MHD + NS group showed significant improvements in liver steatosis indices and inflammation.
Mariana Di Lorenzo, Luca Pipicelli, Laura Aurino, Concetta Sozio, Anna Palmiero, Domenico Palmieri, Marta Lombardi, Bruna Guida, Mariarosaria Santillo, Maria Serena Lonardo, Giuliana La Rosa, Simona Damiano   +11 more
wiley   +1 more source

Correction: De Novo Cost‑Effectiveness Model Framework for Nonalcoholic Steatohepatitis-Modeling Approach and Validation. [PDF]

Pharmacoeconomics
Gal P, Feldmajer G, Augusto M, Gani R, Hook E, Bullement A, Philips Z, Smith I.   +7 more
europepmc   +1 more source

S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis

, 2013
Marcelo G. de Oliveira, Daniel Ferraz de Campos Mazo, Isabel Veloso Alves Pereira, Bruno Cogliati, José Tadeu Stefano, Souza, Fabíola Rabelo, Carrilho, Cláudia P. Oliveira, Fabiana Roberto Lima, Venâncio Avancini Ferreira Alves   +10 more
openalex   +2 more sources

A geriatrician's approach to managing the complex older adult with obesity

Obesity, Volume 33, Issue S1, Page 41-56, November 2025.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source

Burden and trends of nonalcoholic steatohepatitis-related liver cancer in China: A population-based observational study using GBD 2021 data. [PDF]

Medicine (Baltimore)
Xiang MX, Yan P, Lan B, Deng JB, Tan J.
europepmc   +1 more source

Fibulin Family Members: New Players in Liver Fibrosis and Potential Biomarkers in Chronic Liver Diseases

Hepatology Research, Volume 55, Issue 11, Page 1425-1436, November 2025.
ABSTRACT Chronic liver diseases (CLD) arising from various etiologies including viral hepatitis, excessive alcohol intake, alcoholic associated liver disease (ALD) and metabolic dysfunction‐associated steatotic liver disease (MASLD), are associated with persistent hepatic injury ultimately resulting in fibrosis.
Fidaa Bouezzedine, Célia Thomas, Nathalie Théret   +2 more
wiley   +1 more source

Punicalagin relieves hepatic injury by antioxidation and enhancement of autophagy in diet-induced nonalcoholic steatohepatitis. [PDF]

Sci Rep
Ma L, Sun H, Xiang N, Xu Q.
europepmc   +1 more source