Results 211 to 220 of about 9,424,993 (263)

Advances in Cytosolic dsRNA Sensing of Viral Infections

Immunology &Cell Biology, EarlyView.
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley   +1 more source

Spatially resolved profiling of steroid nuclear receptors reveals a role for the disordered N-terminal domains in genome targeting and AP-1 interaction. [PDF]

Genome Res
Zigdon I, Shoham A, Mindel V, Manadre W, Jan D, Krupkin B, Yahav Har-Shai D, Antebi Y, Barkai N.   +8 more
europepmc   +1 more source

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

Immunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton, Bernadette M. Saunders   +1 more
wiley   +1 more source

AVIDbase: A biologically accurate structural dataset of nanobody-antigen complexes. [PDF]

Protein Sci
Medved T, Lah J, Miličić G, Hadži S.
europepmc   +1 more source

Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines

Immunology, EarlyView.
This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw, Aytenew Atnaf, Bantayehu Addis Tegegne, Abebe Fenta, Bantegzie Selabat, Temesgen Baylie, Yonatan Kindie, Zigale Hibstu Teffera, Mekuriaw Belayneh, Mohammed Jemal, Adane Adugna   +10 more
wiley   +1 more source

A Novel Pathogenic <i>CHD7</i> Splice-Site Variant in a Neonate with CHARGE Syndrome Identified by Blood RNA Analysis. [PDF]

Ann Lab Med
Yu S, Jang JH, Yang M, Chang YS, Kim H, Jang MA.   +5 more
europepmc   +1 more source

Horizontal gene transfer and reciprocal chimerism in Compactonostoc (Nostocales, Cyanobacteriophyta) with evidence for two new species in the genus

Journal of Phycology, EarlyView.
Abstract The genus Nostoc has long been known to be polyphyletic, and recent taxonomic work has segregated several Nostoc‐like lineages into new genera, including Compactonostoc. Until now, C. shennongjiaensis was the only described species in the genus.
Daniel Al Fatayri, Joseph M. Grillo, Jeffrey R. Johansen   +2 more
wiley   +1 more source

Noncanonical chromosomal-end-specific telomeric repeat arrays in naturally telomerase-negative yeasts. [PDF]

Nucleic Acids Res
Brejová B, Hodorová V, Lichancová H, Gafurov A, Bujna D, Brázdovič F, Červenák F, Petrík T, Hegedűsová E, Forgáčová Jakúbková M, Neboháčová M, Tomáška Ľ, Sipiczki M, Vinař T, Nosek J.   +14 more
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Sebaceous Nevus Harboring an HRAS p.Ala11_Gly12dup Variant. [PDF]

J Dermatol
Hashimoto S, Yoshioka A, Hanafusa H, Kubo A.   +3 more
europepmc   +1 more source