Results 241 to 250 of about 224,829 (339)

Analysis of Human Uniparental Embryonic Stem Cells Reveals New Putative Imprinted Loci

Cell Proliferation, EarlyView.
To identify novel imprinted genes, parthenogenetic, androgenetic and biparental human embryonic stem cells and their differentiated neural progenitors were analysed by methylome and transcriptome profiling. This approach uncovered 12 putative novel imprinted genes, including a clustered region on chromosome 19, expanding the current catalogue of ...
Shay Kinreich, Nissim Benvenisty
wiley   +1 more source

The landscape of long noncoding RNA during cutaneous squamous cell carcinoma progression. [PDF]

Br J Dermatol
Bone M, Schreyer D, Treanor-Taylor M, Proby CM, Harwood CA, Leigh IM, Bailey P, Inman GJ.   +7 more
europepmc   +1 more source

Extracellular vesicle microRNAs are biomarkers of focal epilepsy but not epilepsy‐related respiratory dysfunction

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the diagnostic value of a set of preselected candidate microRNAs (miRNAs) extracted from plasma‐based extracellular vesicles (EVs) to identify patients with seizure‐related respiratory dysfunction. Methods A two‐step design was applied.
Sylvain Rheims, Hayet Kouchi, Florence Busato, Stanislas Lagarde, David Derbala, Sébastien Boulogne, Mathilde Leclercq, Jessica Chenais, Sandrine Bouvard, Fabrice Bartolomei, Laurent Bezin, Jorg Tost   +11 more
wiley   +1 more source

Exosome-transmitted long noncoding RNA SNHG1 promotes prostate cancer bone metastasis via YBX1/MMP16 axis. [PDF]

Cell Death Discov
Yang T, Luo J, Long Z, Wu J, Chen W, Zhou X, Zou L, Cen S, Zhong C, Lu J, Zheng P, Wei A, Lv D, Mao X.   +13 more
europepmc   +1 more source

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

Epilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri, Oluyomi Adesoji, Roland Krause, Patrick May, Holger Lerche, Albert Becker, Daniela Grimm, International League Against Epilepsy Consortium on Complex Epilepsies, Michael Nothnagel, Herbert Schulz   +9 more
wiley   +1 more source

Investigating the role of the <i>Listeria monocytogenes</i> noncoding RNA Rli47 during the response to environmental stressors. [PDF]

FEMS Microbes
Tibbs-Cortes BW, Strathman-Runyan JL, Schmitz-Esser S.   +2 more
europepmc   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Mitochondrial Fragmentation and Long Noncoding RNA <i>MALAT1</i> in Diabetic Retinopathy. [PDF]

Int J Mol Sci
Kowluru RA, Kumar J.
europepmc   +1 more source

Risk of cardiovascular disease and mortality among women with endometriosis: Genetic insights

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Maria I. Zervou, Theoni B. Tarlatzi, Basil C. Tarlatzis, George N. Goulielmos   +3 more
wiley   +1 more source

Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics

The FEBS Journal, EarlyView.
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang, Sen Yang, Minyoung Cho, Kwangsik Nho, José‐Manuel Baizabal, Hui‐Chen Lu   +5 more
wiley   +1 more source