Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Correction to 'Long Noncoding RNA Highly Upregulated in Liver Cancer Promotes Epithelial-to-Mesenchymal Transition Process in Oral Squamous Cell Carcinoma'. [PDF]
europepmc +1 more source
Association of long noncoding RNA MEG3 genetic variants with the risk of diabetic neuropathy. [PDF]
Fan YC +5 more
europepmc +1 more source
Recovery From Anorexia Nervosa: A Concept Analysis
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley +1 more source
Long Noncoding RNA uc173 is a Novel Regulator of Mitochondrial Metabolism Driving Intestinal Mucosal Growth. [PDF]
Xiao L +9 more
europepmc +1 more source
Novel Liquid Biopsy in Gastrointestinal Cancers
ABSTRACT Gastrointestinal (GI) cancers represent a significant global health burden, being among the leading causes of cancer‐related deaths. The prognosis for patients remains unsatisfactory, largely because most cancers are detected at advanced stages.
Li‐Chun Chang +2 more
wiley +1 more source
The long noncoding RNA VIM-AS1 and nucleoporin Nup358/RanBP2 regulate SMAD nuclear accumulation during TGF-β signaling. [PDF]
Rodrigues-Junior DM +8 more
europepmc +1 more source
Structural variation drives rhizome innovation and adaptive divergence in sister Medicago species
Chromosome‐scale genome analysis, population resequencing, stress‐responsive transcriptomes and functional assays showed that coding and regulatory structural variants, especially gene duplications and noncoding presence‐absence variants, underlie rhizome formation in alpine Medicago archiducis‐nicolai and contrasting xeric adaptation in its non ...
Hongyin Hu +14 more
wiley +1 more source
Restrictor slows RNAPII elongation to promote termination at noncoding RNA loci. [PDF]
Mimoso CA +4 more
europepmc +1 more source

