Results 271 to 280 of about 224,829 (339)

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

<i>VILMIR</i> is a <i>trans</i>-acting long noncoding RNA that enhances the host interferon response in human epithelial cells. [PDF]

J Virol
John K, Smith E, Istishin A, Mahmood N, Diveley K, Tollison TS, Carpenter S, Peng X.   +7 more
europepmc   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Comparative Transcriptomics Reveals Novel and Differential Long-Noncoding RNA Responses Underlying Interferon-Mediated Antiviral Regulation in Porcine Alveolar Macrophages. [PDF]

Pathogens
Li J, Adeyemi O, Miller LC, Sang Y.
europepmc   +1 more source

A Computational Framework to Infer Human Disease-Associated Long Noncoding RNAs

, 2014
Ming-Xi Liu, Xing Chen, Geng Chen, Qinghua Cui, Guiying Yan   +4 more
openalex   +2 more sources

Severe Periodontitis is Associated With Recurrent Cardiovascular Events—A 10‐Year Longitudinal Cohort Study

Journal of Periodontal Research, EarlyView.
One thousand and two patients with cardiovascular disease (CVD) were observed over 10 years. Data were collected from 792 study participants. Severe periodontitis proved to be an independent risk factor for new cardiovascular events. Tooth brushing more than once a day and performing interdental hygiene were associated with decreased risk.
Stefan Reichert, Selina Rehm, Axel Schlitt, Susanne Schulz   +3 more
wiley   +1 more source

RAP proteins regulate apicoplast noncoding RNA processing in Plasmodium falciparum. [PDF]

Cell Rep
Hollin T, Chahine Z, Abel S, Banks C, Pasaje CFA, Lenz T, Prudhomme J, Ybanez CM, Abbaszadeh AS, Niles JC, Florens L, Le Roch KG.   +11 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Correction: Upregulation of long noncoding RNA GCC2-AS1 facilitates malignant phenotypes and correlated with unfavorable prognosis for lung adenocarcinoma. [PDF]

Front Oncol
Yu F, Liang M, Wu W, Huang Y, Zheng J, Zheng B, Chen C.   +6 more
europepmc   +1 more source

Long noncoding RNA MALAT1 promotes uveal melanoma cell growth and invasion by silencing of miR-140.

, 2016
Lei Sun, Peng Sun, Qiying Zhou, Xiang‐Chun Gao, Qing Han   +4 more
openalex   +1 more source