Results 191 to 200 of about 10,340,521 (282)

Extracellular and Membrane Protein: Structure, Biological Functions, Diseases, and an Emerging Modality for Drug Discovery

MedComm, Volume 7, Issue 4, April 2026.
Targeted protein degradation represents a paradigm shift from traditional protein inhibition to complete protein elimination. This is achieved through three main strategies for degrading extracellular and membrane proteins: recruitment of cell‐surface LTRs, engagement of intracellular proteins, and receptor‐independent mechanisms.
Mengqing Zhao, Wenhao Yin, Jianjian Han, Huimin Wang, Zheng Liu, Lilong Liu, Wuxiang Mao   +6 more
wiley   +1 more source

Clinical and social determinants of cardiovascular risk in a population with chronic noncommunicable diseases in Maicao, La Guajira, Colombia: 2024. [PDF]

PLoS One
Angarita-Melo PT, Panche-Castellanos K, Rizo-Tello VZ, Forero-Torres AY, Porras-Ramírez A.   +4 more
europepmc   +1 more source

Dynamic T‐Cell Reprogramming Modulates the Treatment Outcome of Neoadjuvant Immunochemotherapy in Non‐Small‐Cell Lung Cancer

MedComm, Volume 7, Issue 4, April 2026.
We explored the responding mechanisms associated with pathological responsiveness to neoadjuvant immunochemotherapy. CD8+ T‐cell subsets, including effect memory T (Tem), effector T (Teff), resident memory T (Trm), as well as exhausted T cells (Tex), showed higher clonality and diversity in responders, and both novel and pre‐existing clonal expansion ...
Rui Jin, Anhao Tian, Weina Lu, Qiyuan Wang, Xiuzhen Li, Sai Zhang, Guanxin Xu, Kai Zhu, Peng Li, Jianan Li, Wei Chen, Weiwei Yin, Wen Li, Yang Xia   +13 more
wiley   +1 more source

Noncommunicable diseases attributed to low levels of physical activity in Brazil: an epidemiologic Global Burden of Disease Study. [PDF]

Rev Assoc Med Bras (1992)
Maciel EDS, Pontes-Silva A, Figueiredo FWDS, Franco SCA, Quaresma FRP, Nascimento-Ferreira MV.   +5 more
europepmc   +1 more source

Paediatric Primary Care Across Europe: A Survey of 42 Countries

Acta Paediatrica, Volume 115, Issue 4, Page 821-831, April 2026.
ABSTRACT Aim This study provides an updated overview of primary care for children and adolescents across Europe, investigating how systems are evolving and identifying progress and persistent gaps in healthcare models, workforce challenges and digital health integration.
Nora Karara, Antonio Corsello, Stefano del Torso, Adamos Hadjipanayis, Christine Magendie, Diego van Esso, Zachi Grossman, on behalf of the European Academy of Paediatrics and the European Confederation of Primary Care Paediatricians   +7 more
wiley   +1 more source

A systematic review and meta-analysis of pharmacy education and practice on prevention and management of noncommunicable diseases in ASEAN countries. [PDF]

Sci Rep
Olson PS, Sawangjit R, Tan BK, Seesin T, Setiawan CH, Watcharadamrongkun S, Van Hung N, Sibounheuang P, Kifli N, Kanjanasilp J, Sookaneknun S, Jungnickel PW, Do T, Ploylearmsang C.   +13 more
europepmc   +1 more source

The Role of Health Literacy in Adults' Dental Service Utilisation: A Scoping Review

Community Dentistry and Oral Epidemiology, Volume 54, Issue 2, Page 133-145, April 2026.
ABSTRACT Objectives Health literacy refers to an individual's ability to understand health information, navigate healthcare systems, make informed decisions and adopt health‐promoting behaviours. The scoping review examined the available literature to explore adults' health literacy levels, health literacy measurements, and the role of health literacy ...
Xuanyun Lu, Sucharita Nanjappa, Thushani Indumani Devi Wijesiri, Peter Mossey, Siyang Yuan   +4 more
wiley   +1 more source

Association between depression and medication adherence in noncommunicable diseases: a narrative review. [PDF]

Korean J Fam Med
Hisan UK, Widjanarko B, Sriatmi A, Shaluhiyah Z.   +3 more
europepmc   +1 more source

Development and Validation of a Culturally Adapted Patient‐Reported Experience Measure for Diabetes Care in Thailand: Mixed‐Methods Study

Health Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background Patient‐centred care is essential for managing Type 2 diabetes, as it relies on understanding patients’ experiences and perspectives. However, in Thailand, no culturally adapted patient‐reported experience measure (PREM) exists to capture these insights and support quality improvement in diabetes care.
Soe Sandi Tint, Nida Buawangpong, Wichuda Jiraporncharoen, Myo Zin Oo, Nutchar Wiwatkunupakarn, Kittipan Rerkasem, Kanokwan Kulprachakarn, Hataichanok Chuljerm, Timothy E. O'Brien, Rohini Mathur, Petch Rawdaree, Chaisiri Angkurawaranon   +11 more
wiley   +1 more source

Oral Health and Noncommunicable Diseases (NCDs). [PDF]

Int Dent J
FDI World Dental Federation.
europepmc   +1 more source