Sources of Variation in Fecal Haptoglobin in a Population of Wild Capuchin Monkeys (Cebus imitator)
Fecal haptoglobin values show significant seasonal variation in wild capuchin monkeys. Values are highest, and most variable in the early‐mid dry season, when fruit is typically scarce and water sources are standing pools, which can accumulate pathogens.
Raquel Hernández‐Rojas +6 more
wiley +1 more source
A Utility of Volume Expander Plasma in Nonhuman Primate Transplantation Models. [PDF]
Watanabe G +4 more
europepmc +1 more source
Nonclinical Considerations for Support of Pregnancy and Lactation in Clinical Trials
ABSTRACT Background Pregnant and breastfeeding individuals remain underrepresented in clinical drug development, leaving health care providers and patients with limited data to inform treatment decisions. Current practice relies heavily on nonclinical developmental and reproductive toxicity (DART) studies in animals, while clinical trials typically ...
Dinesh Stanislaus +18 more
wiley +1 more source
Optic Nerve Head Spatial Transcriptomic Change in Nonhuman Primate Early Experimental Glaucoma. [PDF]
Williams G +7 more
europepmc +1 more source
Epigenetic Aging in Brain Tissue of the Self‐Fertilizing Vertebrate, Kryptolebias marmoratus
Using the self‐fertilizing vertebrate Kryptolebias marmoratus, we developed an epigenetic clock from brain tissue that predicts chronological age with high accuracy, demonstrating that DNA methylation changes consistently with age even in the near absence of genetic variation. The 40 age‐associated CpG sites identified map to genes with conserved roles
Justine Bélik, Frédéric Silvestre
wiley +1 more source
Expression of Human Thrombomodulin Prevents Early Thrombocytopenia and Thrombotic Microangiopathy in Pig-to-Nonhuman Primate Orthotopic Liver Xenotransplantation. [PDF]
Zhang Z +17 more
europepmc +1 more source
Landscape wetness and beaver wetlands enhance environmental prevalence of Francisella spp.
Abstract Identifying the contributions of biotic and abiotic factors in pathogen transmission is essential to mitigate vector‐borne and zoonotic disease risk. Francisella tularensis is the etiological agent of the infectious disease tularemia in wildlife and humans. Environmental factors driving transmission in wildlife, including the role of hares and
Lovisa Hökby +9 more
wiley +1 more source
Transcranial Focused Ultrasound Modulates Visual Thalamus in a Nonhuman Primate Model. [PDF]
Yu K, He B.
europepmc +1 more source
Decoding the Factor H‐Related Proteins: Gatekeepers of Complement Dysregulation in AMD
This review will explore the role of the factor H‐related (FHR) proteins in age‐related macular degeneration (AMD), their accumulation in the outer blood/retinal barrier, and how they may contribute to barrier dysfunction and inflammation. ABSTRACT Age‐related macular degeneration (AMD) is the third most common form of blindness in the Western world ...
Jiaqi Tang +2 more
wiley +1 more source
Selective impact on regulatory T cells with sustained functional phenotypes by the interleukin-2 mutein VIS171 in a nonhuman primate model. [PDF]
Schiliró D +20 more
europepmc +1 more source

