Results 121 to 130 of about 111,518 (268)

Early Maturation of Heart Rate Variability in Very Preterm Infants Depends on Neonatal Factors and Is Associated With Neurodevelopmental Risk

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study investigated central autonomic network maturation deviations using a previously defined machine learning model set to estimate a functional maturation age (FMA) from heart rate variability (HRV) analysis. We investigated whether these deviations were associated with maternal, fetal, perinatal, or postnatal complications and with
Léa Bonneau, Cyril Flamant, Maxime Esvan, Jean Michel Roué, Géraldine Favrais, Géraldine Gascoin, Sandie Cabon, Fabienne Porée, Guy Carrault, Patrick Pladys   +9 more
wiley   +1 more source

Noninvasive prenatal testing detected acute myeloid leukemia in paucisymptomatic pregnant patient

Clinical Case Reports, 2020
To the authors' best knowledge, this is the first report of acute myeloid leukemia (AML) detected by noninvasive prenatal testing. This was an aggressive case that otherwise would have been difficult to characterize due to disadvantages of "gold‐standard"
Laura Yissel Rengifo, Lucienne Michaux, Johan Maertens, Thomas Tousseyn, Liesbeth Lenaerts, Joris Robert Vermeesch, Peter Vandenberghe, Barbara Dewaele   +7 more
doaj   +1 more source

NIPTmer : rapid k-mer-based software package for detection of fetal aneuploidies [PDF]

, 2018
Non-invasive prenatal testing (NIPT) is a recent and rapidly evolving method for detecting genetic lesions, such as aneuploidies, of a fetus. However, there is a need for faster and cheaper laboratory and analysis methods to make NIPT more widely ...
Brison, Nathalie, Kaplinski, Lauris, Krjutskov, Kaarel, Kurg, Ants, Palta, Priit, Paluoja, Priit, Peters, Maire, Roost, Anne Mari, Salumets, Andres, Sauk, Martin, Teder, Hindrek, Ustav, Eva-Liina, Vermeesch, Joris R., Zilina, Olga   +13 more
core   +3 more sources

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

British Journal of Pharmacology, EarlyView.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu, Yanyan Zhang, Meiling Shan, Jiaqi Cao, Zihan Fan, Zhaoxia Xu, Xiaozhen Ding, Xiaodong Liu, Lijun Shi   +8 more
wiley   +1 more source

Novel mutation in CCBE 1 as a cause of recurrent hydrops fetalis from Hennekam lymphangiectasia-lymphedema syndrome-1. [PDF]

, 2018
Whole exome sequencing (WES) was used to determine the etiology of recurrent hydrops fetalis in this case of Hennekam lymphangiectasia-lymphedema syndrome-1.
Andreasen, Tara S, Lamale-Smith, Leah M, Mao, Rong, Melber, Dora J, Miller, Christine E, Moore, Thomas R, Tvrdik, Tatiana, Woelkers, Douglas A   +7 more
core  

Fetal Fraction Signatures: A Quality Control Tool to Detect Potentially Confounding Situations in NonInvasive Prenatal Diagnosis of Monogenic Conditions

Clinical Genetics, EarlyView.
Noninvasive prenatal diagnosis for monogenic diseases (NIPD‐M) to detect inherited mutations is performed in parallel with fetal fraction signatures, to detect various anomalies that may compromise diagnosis. An extra regression analysis may be necessary to resolve mosaic situations. ABSTRACT Noninvasive prenatal diagnosis relies on the analysis of the
Jean‐Louis Blouin, Claudine Rieubland, Thierry Nouspikel   +2 more
wiley   +1 more source

A new era in prenatal care: non-invasive prenatal testing in Switzerland

Swiss Medical Weekly, 2014
QUESTIONS UNDER STUDY: Prenatal care has been significantly influenced by the introduction of non-invasive prenatal testing (NIPT) for aneuploidies in 2012. The aim of this study was to describe the current impact of NIPT on prenatal care.
Gwendolin Manegold-Brauer, Anjeung Kang Bellin, Sinuhe Hahn, Christian De Geyter, Johanna Buechel, Irene Hoesli, Olav Lapaire   +6 more
doaj   +1 more source

For your interest?:The ethical acceptability of using non-invasive prenatal testing to test 'purely for information' [PDF]

, 2014
Non-invasive prenatal testing (NIPT) is an emerging form of prenatal genetic testing that provides information about the genetic constitution of a foetus without the risk of pregnancy loss as a direct result of the test procedure.
Clarke, Angus J, Deans, Zuzana, Newson, Ainsley J   +2 more
core   +3 more sources

Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect

Journal of Child Psychology and Psychiatry, EarlyView.
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson, Hanna R. Wright, Jorden E. Jacinto Schreeder, Joel T. Nigg, Elinor L. Sullivan   +4 more
wiley   +1 more source

Non-invasive Prenatal Testing: New Prospects to Personalized Prenatal Medicine

Bihdād, 2019
Recent works have discovered, the focus on prenatal diagnosis have now opened up new start for a more detailed analysis of fetal genetics and genomics.
Fatemeh Mansouri
doaj