Results 221 to 230 of about 111,518 (268)

Impact of the new government‐involved noninvasive prenatal testing certification system on the awareness of pregnant women about noninvasive prenatal testing in Japan

The journal of obstetrics and gynaecology research
In Japan, noninvasive prenatal testing (NIPT) has been performed by facilities accredited by the Japanese Society of Obstetrics and Gynecology since 2013. However, since 2016, with the implementation of NIPT, which can only be performed by blood sampling,
N. Shirato, Akihiko Sekizawa, K. Miyagami, Miwa Sakamoto, Takahiro Yamada, Tatsuko Hirose, Shin Ikebukuro, Takeshi Nakamura, Akane Mizutani, Mai Ikemoto, Mikiko Izum, Hitomi Seino, S. Yamada, N. Suzumori, H. Yoshihashi, O. Samura, Hideaki Sawai, H. Sago, Torayuki Okuyama   +18 more
semanticscholar   +1 more source

How I use noninvasive prenatal testing for red blood cell and platelet antigens.

Blood
Alloimmunization during pregnancy occurs when a mother produces antibodies against fetal antigens, leading to complications like hemolytic disease of the fetus and newborn (HDFN) and fetal and neonatal alloimmune thrombocytopenia (FNAIT).
R. M. van ’t Oever, E. Verweij, M. de Haas   +2 more
semanticscholar   +1 more source

Contribution of maternal mosaicism to false-positive chromosome X loss associated with noninvasive prenatal testing

Journal of Maternal-Fetal & Neonatal Medicine, 2022
Objective To report the frequency of maternal mosaicism contributing to false-positive chromosome X loss associated with noninvasive prenatal testing (NIPT) at a single center.
Junhui Wan, Ru Li, Fa-tao Li, Qiuxia Yu, Dan Wang, Xiuhong Sun, Yong-ling Zhang, X. Jing, Xuewei Tang, Gui-lan Chen, F. Jiang, Fucheng Li, F. Fu, Yan Li, Lina Zhang, C. Yi, Jian Li, Dongzhi Li, C. Liao   +18 more
semanticscholar   +1 more source

Machine learning‐enhanced noninvasive prenatal testing of monogenic disorders

Prenatal Diagnosis
Single‐nucleotide variants (SNVs) are of great significance in prenatal diagnosis as they are the leading cause of inherited single‐gene disorders (SGDs).
Noa Liscovitch-Brauer, R. Mesika, T. Rabinowitz, Hadas Volkov, Meitar Grad, R. Matar, L. Basel-Salmon, Oren Tadmor, Amir Beker, N. Shomron   +9 more
semanticscholar   +1 more source

Noninvasive prenatal testing of Duchenne muscular dystrophy in a twin gestation

Prenatal Diagnosis, 2022
Haplotype‐based assay has been proved efficient in noninvasive prenatal testing for various monogenic disorders in singleton pregnancies. However, its application in twin pregnancies is still blank.
L. Kong, Shaojun Li, Zhen-hua Zhao, Jun Feng, Li'na Liu, Weiqin Tang, Haichuan Zhang, Di Wu, Luming Sun, X. Kong   +9 more
semanticscholar   +1 more source

Noninvasive prenatal testing.

Australian family physician, 2016
Noninvasive prenatal testing (NIPT) has marked a revolution in aneuploidy screening because it allows a simple maternal blood test to detect Down syndrome in a fetus with a very high level of accuracy (at least 99.5% with a false-positive rate of 0.2%).To describe the new tests that have become available and their place in antenatal screening to help ...
Jane, Woolcock, Rosalie, Grivell
openaire   +1 more source

Noninvasive prenatal testing of hereditary colorectal cancer syndromes using cell‐free DNA in maternal plasma

Prenatal Diagnosis, 2022
This study aimed to establish a practical protocol for early noninvasive prenatal testing (NIPT) for fetuses at risk of Peutz‐Jeghers syndrome or familial adenomatous polyposis, two classical types of hereditary colorectal cancer syndromes, for risk ...
Yao Wang, Suqing Li, Di Wu, Hongli Yan
semanticscholar   +1 more source

Noninvasive Prenatal Testing (NIPT): Current Status

2020
The concept of circulating fetal cells in the mother was first discussed by a German pathologist, Georg Schmorl, who identified fetal trophoblasts in lungs of eclamptic women on autopsy in 1893 [1]. After this suggestion there was a hiatus of nearly 100 years before any development could be made in the field.
K. Aparna Sharma, Neerja Bhatla
openaire   +1 more source

Noninvasive Prenatal Testing: An Update on Prenatal Screening and Testing Options

NeoReviews, 2014
The landmark discovery that cell-free fetal DNA was present in maternal plasma paved the way for significant changes in prenatal screening and diagnosis. Although traditional screening approaches relied on measuring maternal serum markers and ultrasound findings, analyzing cell-free fetal DNA held the promise of increasing the sensitivity and ...
Sarah C. Harris, Neeta L. Vora
openaire   +1 more source

Noninvasive prenatal testing beyond genomic analysis

Current Opinion in Obstetrics & Gynecology, 2016
The discovery of cell-free fetal DNA in maternal blood enabled the development of DNA-based noninvasive prenatal testing. Noninvasive prenatal testing for chromosomal aneuploidy detection was first applied for clinical use a few years ago, resulting in a paradigm shift in prenatal testing.
Winnie W I, Hui, Rossa W K, Chiu
openaire   +2 more sources