Results 61 to 70 of about 2,711,073 (164)

Ultrasound and SNP-based cell-free DNA zygosity testing in twin pregnancies

The Journal of Maternal-Fetal & Neonatal Medicine
Introduction The importance of prenatal determination of chorionicity for the management of twin pregnancies is well recognized. However, research on the contribution of prenatal evaluation of zygosity to the management of twins is limited.
Ruben Quintero, K. Joseph Hurt, Neeta L. Vora, Neil S. Seligman, Gerard P. Reilly, Myra J. Wick, Samuel B. Wolf, Maeve Hopkins, Thomas Westover, Homa K. Ahmadzia, Camille Kanaan, Andrei Rebarber, Eftichia V. Kontopoulos, Jingwen Zhang, Melissa Egbert, Sophia Vourthis, Ashley Cantu-Weinstein, Jessica L. Saben, Russ Jelsema, Vivienne Souter, Clark T. Johnson, Peter Benn   +21 more
doaj   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Fetal Brain Abnormalities in Trisomy 21 and Associated Neurodevelopmental Outcome: Key Factors to Identify Differences in Neurodevelopmental Outcome?

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Trisomy 21 (T21) is associated with various neurological impairments. However, the mechanisms of fetal brain development in T21 and their impact on neurodevelopmental outcomes remain unclear, limiting prenatal counseling. Therefore, this study aims to assess neuropathological changes in fetuses with T21 and the associated ...
Christina Haberl, Pilar Palmrich, Eva Karner, Patric Kienast, Sarah Glatter, Florian Heinzl, Philipp Moser, Daniela Prayer, Gregor Kasprian, Julia Binder   +9 more
wiley   +1 more source

A new fetal RHD genotyping test : costs and benefits of mass testing to target antenatal anti-D prophylaxis in England and Wales [PDF]

, 2011
Background Postnatal and antenatal anti-D prophylaxis have dramatically reduced maternal sensitisations and cases of rhesus disease in babies born to women with RhD negative blood group.
Szczepura Ala, Szczepura, Ala, Freeman Karoline, Karoline Freeman, Ala Szczepura, Freeman, K., Osipenko, L., Osipenko, Leeza, Freeman, Karoline, Leeza Osipenko, Osipenko Leeza, Szczepura, Ala; id_orcid   +11 more
core   +2 more sources

A review of evidence on non-invasive prenatal diagnosis (NIPD) : tests for fetal RHD genotype [PDF]

, 2007
This report concentrates on three main areas. First and foremost, we set the background context for RhD NIPD in prenatal care. While the methodology chapter describes how the literature review was carried out and how additional information was collected,
Clay, Diane, Hyde, Julia, Szczepura, Ala, Osipenko, Leeza, HASH(0x55a67fc1f4e0), Freeman, Karoline   +5 more
core  

Application value of NIPT for uncommon fetal chromosomal abnormalities

Molecular Cytogenetics, 2020
Objective To investigate the clinical value of noninvasive prenatal testing (NIPT) for fetal chromosomal deletion, duplication, and sex chromosome abnormalities.
Lianli Yin, Yinghua Tang, Qing Lu, Aiping Pan, Mingfang Shi   +4 more
doaj   +1 more source

Early noninvasive prenatal paternity testing by targeted fetal DNA analysis

Scientific Reports, 2023
Today the challenge in paternity testing is to provide an accurate noninvasive assay that can be performed early during pregnancy. This requires the use of novel analytical methods capable of detecting the low fraction of circulating fetal DNA in ...
Géraldine Damour, Karine Baumer, Hélène Legardeur, Diana Hall   +3 more
doaj   +1 more source

Spectrum of Congenital Malformations in Sex Chromosome Tetrasomies and Pentasomies: A Systematic Review

Andrology, EarlyView.
ABSTRACT Sex chromosome aneuploidies represent a heterogeneous group of chromosomal conditions, in which phenotypic complexity generally increases with the number of supernumerary sex chromosomes. While Turner syndrome and sex chromosome trisomies are relatively well characterized, less is known about congenital malformations in sex chromosome ...
Anna Colding, Jannie Traberg, Inger Lily Hjuler Dorf, Anne Skakkebæk   +3 more
wiley   +1 more source

Serum screening and fetal karyotype of cases at high risk in noninvasive prenatal testing.

, 2022
Serum screening and fetal karyotype of cases at high risk in noninvasive prenatal testing.
Huayu Luo (12418614), Wuyan Huang (12418611), Liqing Hu (9409143), Gefei Xiao (12418608), Yanling Zhao (291207), Guoqing Wang (128352)   +5 more
core   +1 more source

Non-Invasive Prenatal Testing (NIPT): A Paradigm Shift in Prenatal Care

International Journal of Preventive Medicine
Prenatal screening has undergone a profound transformation with the emergence of Non-Invasive Prenatal Testing (NIPT), a technology that analyzes cell-free fetal DNA (cffDNA) in maternal blood to detect common chromosomal abnormalities.
Ram K. Garg, Yogesh Kumar, Ram Niwas, Jitendra Singh   +3 more
doaj   +1 more source