Results 51 to 60 of about 76,326 (312)

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Noninvasive assessment of inspiratory muscle neuromechanical coupling during inspiratory threshold loading [PDF]

, 2019
Diaphragm neuromechanical coupling (NMC), which reflects the efficiency of conversion of neural activation to transdiaphragmatic pressure (Pdi), is increasingly recognized to be a useful clinical index of diaphragm function and respiratory mechanics in ...
Estrada Petrocelli, Luis Carlos, Jané Campos, Raimon, Jolley, J, Lozano García, Manuel, Moxham, John, Rafferty, Gerrard F., Torres Cebrián, Abel   +6 more
core   +2 more sources

Unveiling Localized Heat in Lithium‐Ion Cells for Intelligent Temperature Sensing

Advanced Energy and Sustainability Research, EarlyView.
Heat generation, thermal responses, and intelligent management in batteries. Lithium‐ion batteries (LIBs) power electric vehicles, portable electronics, and grid‐scale storage, yet their safety, performance, and lifetime are constrained by thermal effects.
Yunke Wang, Yuzhu Yuan, Javed Alam, Guangpeng Zhang, José V. Anguita, Zijian Wang, Kai Yang   +6 more
wiley   +1 more source

Cerebral autoregulation, brain injury, and the transitioning premature infant [PDF]

, 2017
Improvements in clinical management of the preterm infant have reduced the rates of the two most common forms of brain injury, such as severe intraventricular hemorrhage and white matter injury, both of which are contributory factors in the development ...
Mathur, Amit M, Vesoulis, Zachary A
core   +3 more sources

Identification of Exhaled Volatile Organic Compounds Biomarkers for Lung Cancer Under Data‐Limited Conditions Using Data Augmentation and Multi‐View Feature Selection

Advanced Intelligent Discovery, EarlyView.
This work introduces a novel framework for identifying non‐small cell lung cancer biomarkers from hundreds of volatile organic compounds in breath, analyzed via gas chromatography‐mass spectrometry. This method integrates generative data augmentation and multi‐view feature selection, providing a stable and accurate solution for biomarker discovery in ...
Guancheng Ren, Bohao Liu, Zhiyuan Qu, Xue Jiang, Heng Zhao, Danyao Qu, Ruizhi Ning, Chen Su, Taoping Liu, Guangjian Zhang, Weiwei Wu   +10 more
wiley   +1 more source

Predictive significance of the six-minute walk distance for long-term survival in chronic hypercapnic respiratory failure [PDF]

, 2007
Background: The 6-min walk distance ( 6-MWD) is a global marker of functional capacity and prognosis in chronic obstructive pulmonary disease ( COPD), but less explored in other chronic respiratory diseases.
Aida A, Andre P. Hitzl, ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories, Barreiro E, Bittner V, Bowen JB, Budweiser S, Budweiser S, Cano NJ, Cano NJ, Carter R, Casanova C, Chailleux E, Criee CP, Enright PL, Fabbri L, Farre R, Felix Heidtkamp, Frank Heinemann, Fuschillo S, Gustafson T, Highcock MP, Kathrin Schmidbauer, Koechlin C, Kossler W, Lederer DJ, Lloyd-Owen SJ, Marquis K, Mascolo MC, Michael Arzt, Michael Pfeifer, Miyamoto S, Quanjer PH, Rudolf A. Jörres, Sauleda J, Schols AM, Sciurba F, Stephan Budweiser, Stephan Schroll, Vestbo J   +39 more
core   +1 more source

Neonatal Respiration Monitoring System with Synchronized Oxygen Supply and Machine Learning‐Based Breathing Classification

Advanced Intelligent Systems, EarlyView.
The study presents a low‐cost, noninvasive system for real‐time neonatal respiratory monitoring. A flexible, screen‐printed sensor patch captures chest movements with high sensitivity and minimal drift. Combined with machine learning, the system accurately detects breathing patterns and offers a practical solution for neonatal care in low‐resource ...
Gitansh Verma, Eugen Koch, Andreas Dietzel, Shrutidhara Sarma   +3 more
wiley   +1 more source

Factors associated with adherence to noninvasive positive pressure ventilation in amyotrophic lateral sclerosis.

PLoS ONE
IntroductionThis cohort study aimed to investigate the factors associated with noninvasive positive pressure ventilation adherence and assess the long-term effects of noninvasive positive pressure ventilation adherence in patients with amyotrophic ...
Hee Soo Kim, Hyeonseong Woo, Seok-Jin Choi, Jong-Gyu Baek, Ju Seok Ryu, Hyung-Ik Shin, Kyung Seok Park, Jaewon Beom   +7 more
doaj   +1 more source

Long-term home mechanical ventilation using a noninvasive ventilator via tracheotomy in patients with myasthenia gravis: a case report and literature review

Therapeutic Advances in Respiratory Disease, 2023
Neuromuscular diseases (NMD) are indications for long-term home mechanical ventilation (HMV). Noninvasive ventilation is preferred to HMV. However, invasive mechanical ventilation (IMV) is more appropriate if the patient has uncontrollable airway ...
Yanbing Liu, Tao Li, Lei Shi
doaj   +1 more source

Biphasic cuirass ventilation in the escalation of non-invasive ventilation in COVID-19: Case report and review

Monaldi Archives for Chest Disease, 2023
Ventilatory alternatives to prolong noninvasive ventilation in COVID-19 patients are attractive and poorly understood. New devices to deliver negative noninvasive ventilation as biphasic cuirass ventilation (BCV) have been introduced.
Joana Almeida Borges, Antonio M. Esquinas   +1 more
doaj   +1 more source