Results 81 to 90 of about 598,280 (310)

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

open access: yesAnnals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije   +9 more
wiley   +1 more source

Physiologic Effects of Noninvasive Ventilation

open access: yesRespiratory care, 2019
Noninvasive ventilation (NIV) has a number of physiologic effects similar to invasive ventilation. The major effects are to augment minute ventilation and reduce muscle loading.
N. MacIntyre
semanticscholar   +1 more source

Management of pneumothorax in the setting of chronic non-invasive positive pressure ventilation: A case series

open access: yesRespiratory Medicine Case Reports, 2022
There is a growing population of patients who require chronic noninvasive ventilation. While these patients often have no parenchymal lung disease, the use of positive pressure ventilation itself predisposes to both initial and recurrent pneumothoraces ...
Avnee J. Kumar   +2 more
doaj   +1 more source

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome

open access: yesCritical Care, 2019
RationaleOur pilot study suggested that noninvasive ventilation (NIV) reduced the need for intubation compared with conventional administration of oxygen on patients with “early” stage of mild acute respiratory distress syndrome (ARDS, PaO2/FIO2 between ...
Hangyong He   +105 more
semanticscholar   +1 more source

Predictive significance of the six-minute walk distance for long-term survival in chronic hypercapnic respiratory failure [PDF]

open access: yes, 2007
Background: The 6-min walk distance ( 6-MWD) is a global marker of functional capacity and prognosis in chronic obstructive pulmonary disease ( COPD), but less explored in other chronic respiratory diseases.
Aida A   +39 more
core   +1 more source

Guideline for the Detection of Advanced Glycation End Products

open access: yesFood Safety and Health, EarlyView.
This experimental guide focuses on using methods such as GC–MS, LC–MS/MS, and HPLC–MS/MS to detect advanced glycation end products (AGEs) from the Maillard pathway, facilitating investigation of their association with diabetes and cardiovascular diseases. ABSTRACT Advanced glycation end products (AGEs), stable products of nonenzymatic reactions between
Chenxu Bao   +6 more
wiley   +1 more source

Nasal high-flow versus noninvasive ventilation in patients with chronic hypercapnic COPD

open access: yesInternational Journal of COPD, 2019
Background Despite the encouraging results of noninvasive ventilation (NIV) in chronic hypercapnic COPD patients, it is also evident that some patients do not tolerate NIV or do not benefit from it. We conducted a study in which COPD patients with stable,
J. Bräunlich   +13 more
semanticscholar   +1 more source

ERS statement on standardisation of cardiopulmonary exercise testing in chronic lung diseases [PDF]

open access: yes, 2019
The objective of this document was to standardise published cardiopulmonary exercise testing (CPET) protocols for improved interpretation in clinical settings and multicentre research projects.
Aguilaniu   +88 more
core   +3 more sources

Helmet noninvasive ventilation for COVID-19 patients (Helmet-COVID): statistical analysis plan for a randomized controlled trial

open access: yesTrials, 2022
Background Noninvasive respiratory support is frequently needed for patients with acute hypoxemic respiratory failure due to coronavirus disease 19 (COVID-19).
Yaseen Arabi   +24 more
doaj   +1 more source

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