Results 51 to 60 of about 2,043,473 (299)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Effect of wavelength on propagation of high-power femtosecond laser pulses in diamond

Компьютерная оптика
: Numerical modeling of the propagation of high-power femtosecond laser beams in a diamond crystal in the self-focusing mode is carried out. The wavelength of the modeled beams is varied in a wide range (400 nm, 532 nm, 800 nm, and 1064 nm), which ...
T.V. Kononenko, E.V. Zavedeev , K.K. Ashikkalieva, V.I. Konov   +3 more
doaj   +1 more source

Using integrating spheres as absorption cells: path-length distribution and application of Beer's law [PDF]

, 2009
We have modeled the path-length distribution in an integrating sphere used as a multipass optical cell for absorption measurements. The measured radiant flux as a function of analyte concentration is nonlinear as a result, deviating from that expected
Hodgkinson, Jane, Tatam, Ralph P., Masiyano, Dackson, Jane Hodgkinson, Dackson Masiyano, Ralph P. Tatam   +5 more
core   +1 more source

Nonlinear Resonance Absorption in the Laser-Cluster Interaction [PDF]

Physical Review Letters, 2006
Rare gas or metal clusters are known to absorb laser energy very efficiently. Upon cluster expansion the Mie plasma frequency may become equal to the laser frequency. This linear resonance has been well studied both experimentally and theoretically employing pump probe schemes.
Kundu, M., Bauer, D.
openaire   +4 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Ultrafast Nonlinear Optical Response and Carrier Dynamics in Layered Gallium Sulfide (GaS) Single-Crystalline Thin Films

Frontiers in Materials, 2021
Gallium sulfide (GaS) is a layered metal monochalcogenide semiconductor that has recently garnered considerable attention in various fields. In this study, we investigated the nonlinear absorption characteristics of multilayer β-GaS thin films on ...
Haishuang Lu, Haishuang Lu, Yu Chen, Kexin Yang, Yawei Kuang, Yawei Kuang, Zhongguo Li, Yushen Liu, Yushen Liu   +8 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Focusing and absorption of nonlinear oscillations [PDF]

Journées équations aux dérivées partielles, 1993
The Cauchy problem for the dissipative wave equation \[ u_{tt} - \Delta u + u | u |^ p = 0, \quad t > 0, \quad x \in \mathbb{R}^ d \] with fast oscillating initial functions is considered. The problem is a passage of the fast oscillating wave through a focal point, where the wave amplitude is increasing that is predicted by the geometric optics method.
Joly, J. L., Métivier, G., Rauch, J.
openaire   +2 more sources

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source