Results 31 to 40 of about 280,390 (261)

Nonlinear modes in the harmonic PT-symmetric potential

open access: yes, 2012
We study the families of nonlinear modes described by the nonlinear Schr\"odinger equation with the PT-symmetric harmonic potential $x^2-2i\alpha x$. The found nonlinear modes display a number of interesting features. In particular, we have observed that
Dmitry A. Zezyulin   +4 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Quantized‐feedback hands‐off control for nonlinear systems

open access: yesIET Control Theory & Applications, 2021
This paper addresses a quantized feedback hands‐off control for a class of nonlinear systems. Here, [K,KL] sector is constructed with the suitable choice of control‐Lyapunov function.
Ankit Sachan   +4 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Shape Adjustment of a Large Planar Phased Array Antenna With Nonlinear Cable Actuators

open access: yesInternational Journal of Aerospace Engineering
Shape adjustment of large planar phased array antennas is significant because the shape distortion of phased arrays can greatly reduce the antenna’s gain in the observing direction.
Jiyang Zhou   +4 more
doaj   +1 more source

Valuation and Hedging of Contracts with Funding Costs and Collateralization [PDF]

open access: yes, 2014
The research presented in this work is motivated by recent papers by Brigo et al. (2011), Burgard and Kjaer (2009), Cr\'epey (2012), Fujii and Takahashi (2010), Piterbarg (2010) and Pallavicini et al. (2012).
Bielecki, Tomasz R., Rutkowski, Marek
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

DESIGN AND EXPERIMENTAL ANALYSIS OF A NONLINEAR ULTRAHARMONIC VIBRATOR EXCITER

open access: yesJixie qiangdu, 2022
Aiming at the problem that the vibration frequency of conventional vibration exciter is small and can not realize the resonance of high stiffness components, Based on the superharmonic vibration characteristics of nonlinear vibration system, designed a ...
WANG ChengJun   +2 more
doaj  

Data Quality Assessment of Time-Variable Surface Microgravity Surveys in the Southeastern Tibetan Plateau

open access: yesApplied Sciences, 2022
Ground-based time-variable gravimetry with high accuracy is an important approach in monitoring geodynamic processes. The uncertainty of instruments including scale factor (SF) and drift rate are the primary factors affect the quality of observation data.
Qiuyue Zheng   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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