Results 31 to 40 of about 64,424 (261)

Optical bistability in two-dimensional nonlinear composites of coated cylinders with nonlinear core and graded shell

open access: yesEPJ Applied Metamaterials, 2020
The intrinsic optical bistability of the nonlinear composite consisting of coated cylinders with nonlinear core and graded Drude shell is investigated with self-consistent mean-field approximation.
Wu Ya M.   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Research on parallel control of CMAC and PD based on U model

open access: yesAutomatika, 2021
In this paper, the nonlinear U model with time-varying coefficients is investigated and the transformation of the nonlinear model is accomplished by the Newton iterative algorithm. Based on the nonlinear U model, a control algorithm with cerebellar model
Fengxia Xu   +4 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Global Distribution Adjustment and Nonlinear Feature Transformation for Automatic Colorization

open access: yesAdvances in Multimedia, 2018
Automatic colorization is generally classified into two groups: propagation-based methods and reference-based methods. In reference-based automatic colorization methods, color image(s) are used as reference(s) to reconstruct original color of a gray ...
Terumasa Aoki, Van Nguyen
doaj   +1 more source

A 2-DOF-IMC method for suppressing transmission chain vibration of wind power generation system with a clearance

open access: yesAdvances in Mechanical Engineering, 2022
To address the vibration problem caused by gear clearance in the wind drivetrain, a two-degree-of-freedom internal model control (2-DOF-IMC) method was proposed to suppress the clearance’s nonlinear vibration.
Chen-Yang Zhou, Yan-Xia Shen
doaj   +1 more source

Nonlinear Rossby adjustment in a channel: beyond Kelvin waves [PDF]

open access: yesJournal of Fluid Mechanics, 1989
Nonlinear advective adjustment of a discontinuity in free-surface height under gravity and rotation is considered, using the method of contour dynamics. After linear wave-adjustment has set up an interior jet and boundary currents in a wide ([Gt ] one Rossby radius) channel, fluid surges down-channel on both walls, rather than only that wall ...
HERMANN, AJ, RHINES, PB, JOHNSON, ER
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Shape Adjustment of a Large Planar Phased Array Antenna With Nonlinear Cable Actuators

open access: yesInternational Journal of Aerospace Engineering
Shape adjustment of large planar phased array antennas is significant because the shape distortion of phased arrays can greatly reduce the antenna’s gain in the observing direction.
Jiyang Zhou   +4 more
doaj   +1 more source

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