Results 41 to 50 of about 1,793,022 (276)

Nonlinear Drillstring Dynamics Analysis [PDF]

SIAM Journal on Applied Dynamical Systems, 2009
This paper studies the dynamical response of a rotary drilling system with a drag bit, using a lumped parameter model that takes into consideration the axial and torsional vibration modes of the bit. These vibrations are coupled through a bit-rock interaction law.
Germay, Christophe, deWouw, Nathan Van, Nijmeijer, Henk, Sepulchre, Rodolphe   +3 more
openaire   +1 more source

Nonlinear analysis of dynamical complex networks [PDF]

, 2013
Copyright © 2013 Zidong Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited ...
Dong, H, Hu, J, Shen, B, Wang, Z
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Perturbed Keplerian Hamiltonian Systems

International Journal of Differential Equations, 2023
This paper deals with a class of perturbation planar Keplerian Hamiltonian systems, by exploiting the nondegeneracy properties of the circular solutions of the planar Keplerian Hamiltonian systems, and by applying the implicit function theorem, we show ...
Riadh Chteoui
doaj   +1 more source

Four conjectures in Nonlinear Analysis

, 2017
In this chapter, I formulate four challenging conjectures in Nonlinear Analysis. More precisely: a conjecture on the Monge-Amp\`ere equation; a conjecture on an eigenvalue problem; a conjecture on a non-local problem; a conjecture on disconnectedness ...
A. Bahri, AJB Lopes-Pinto, B Ricceri, B Ricceri, B Ricceri, B Ricceri, B Ricceri, B Ricceri, D Passaseo, D Passaseo, E Zeidler, E Zeidler, E. N. Dancer, HH Schaefer, J Saint Raymond, JL Kazdan, JL Kelley, Lars Diening, N Hirano, NI Katzourakis, P Pucci, SI Pohozaev, XL Fan, XL Fan, XL Fan, Zdzisław Denkowski   +25 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Discussion on “Multidimensional Coincidence Points” via Recent Publications

Abstract and Applied Analysis, 2014
We show that some definitions of multidimensional coincidence points are not compatible with the mixed monotone property. Thus, some theorems reported in the recent publications (Dalal et al., 2014 and Imdad et al., 2013) have gaps. We clarify these gaps
Saleh A. Al-Mezel, Hamed H. Alsulami, Erdal Karapınar, Antonio-Francisco Roldán López-de-Hierro   +3 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source