Results 51 to 60 of about 444,118 (261)

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source

Qualitative analysis of fourth-order hyperbolic equations

Frontiers in Applied Mathematics and Statistics
We investigate the qualitative properties of weak solutions to the boundary value problems for fourth-order linear hyperbolic equations with constant coefficients in a plane bounded domain convex with respect to characteristics.
Yuliia Andreieva, Kateryna Buryachenko, Kateryna Buryachenko   +2 more
doaj   +1 more source

Some inequalities and superposition operator in the space of regulated functions

Advances in Nonlinear Analysis, 2019
Some inequalities connected to measures of noncompactness in the space of regulated function R(J, E) were proved in the paper. The inequalities are analogous of well known estimations for Hausdorff measure and the space of continuous functions.
Olszowy Leszek, Zając Tomasz
doaj   +1 more source

A Study of Nonlinear Fractional-Order Boundary Value Problem with Nonlocal Erdelyi-Kober and Generalized Riemann-Liouville Type Integral Boundary Conditions

Mathematical Modelling and Analysis, 2017
We investigate a new kind of nonlocal boundary value problems of nonlinear Caputo fractional differential equations supplemented with integral boundary conditions involving Erdelyi-Kober and generalized Riemann-Liouville fractional integrals.
Bashir Ahmad, Sotiris K. Ntouyas, Jessada Tariboon, Ahmed Alsaedi   +3 more
doaj   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

Longitudinal Changes in Adiposity After a Youth Sport‐Related Knee Injury: Informing Posttraumatic Osteoarthritis Prevention

Arthritis Care &Research, EarlyView.
Objective Youth who experience a sport‐related knee injury have elevated odds of becoming overweight or developing obesity in 3 to 10 years, compounding their risk for posttraumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth ...
Justin M. Losciale, Nuria E. J. Jansen, Christina Y. Le, Leo Lu, Hui Xie, Marienke van Middelkoop, Jackie L. Whittaker   +6 more
wiley   +1 more source

The superposition operator in the space of functions continuous and converging at infinity on the real half-axis

Advances in Nonlinear Analysis, 2019
We will consider the so-called superposition operator in the space CC(ℝ+) of real functions defined, continuous on the real half-axis ℝ+ and converging to finite limits at infinity.
Rzepka Beata, Ścibisz Justyna
doaj   +1 more source

Clinician and Patient Factors Associated With Long‐Term Glucocorticoid Use in People With Rheumatoid Arthritis Receiving Advanced Therapies

Arthritis Care &Research, EarlyView.
Objective Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis Registry were surveyed ...
Michael D. George, George Reed, Matthew D. Kearney, Peter F. Cronholm, Kevin Kane, Jeffrey R. Curtis, Dimitrios A. Pappas, Joel M. Kremer   +7 more
wiley   +1 more source

The influence of thermal and conductive temperatures in a nanoscale resonator

Results in Physics, 2018
In this work, the thermoelastic interaction in a nano-scale resonator based on two-temperature Green-Naghdi model is established. The nanoscale resonator ends were simply supported.
Aatef Hobiny, Ibrahim A. Abbas
doaj   +1 more source