Results 51 to 60 of about 418,531 (262)

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Qualitative analysis of fourth-order hyperbolic equations

Frontiers in Applied Mathematics and Statistics
We investigate the qualitative properties of weak solutions to the boundary value problems for fourth-order linear hyperbolic equations with constant coefficients in a plane bounded domain convex with respect to characteristics.
Yuliia Andreieva, Kateryna Buryachenko, Kateryna Buryachenko   +2 more
doaj   +1 more source

Some inequalities and superposition operator in the space of regulated functions

Advances in Nonlinear Analysis, 2019
Some inequalities connected to measures of noncompactness in the space of regulated function R(J, E) were proved in the paper. The inequalities are analogous of well known estimations for Hausdorff measure and the space of continuous functions.
Olszowy Leszek, Zając Tomasz
doaj   +1 more source

A Study of Nonlinear Fractional-Order Boundary Value Problem with Nonlocal Erdelyi-Kober and Generalized Riemann-Liouville Type Integral Boundary Conditions

Mathematical Modelling and Analysis, 2017
We investigate a new kind of nonlocal boundary value problems of nonlinear Caputo fractional differential equations supplemented with integral boundary conditions involving Erdelyi-Kober and generalized Riemann-Liouville fractional integrals.
Bashir Ahmad, Sotiris K. Ntouyas, Jessada Tariboon, Ahmed Alsaedi   +3 more
doaj   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

The superposition operator in the space of functions continuous and converging at infinity on the real half-axis

Advances in Nonlinear Analysis, 2019
We will consider the so-called superposition operator in the space CC(ℝ+) of real functions defined, continuous on the real half-axis ℝ+ and converging to finite limits at infinity.
Rzepka Beata, Ścibisz Justyna
doaj   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Background/Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs Rheumatoid Arthritis (VARA) Registry.
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source

The influence of thermal and conductive temperatures in a nanoscale resonator

Results in Physics, 2018
In this work, the thermoelastic interaction in a nano-scale resonator based on two-temperature Green-Naghdi model is established. The nanoscale resonator ends were simply supported.
Aatef Hobiny, Ibrahim A. Abbas
doaj   +1 more source