Results 41 to 50 of about 1,810,923 (292)
Why Patterns Appear Spontaneously in Dissipative Systems? [PDF]
, 1999 It is proposed that the spatial (and temporal) patterns spontaneously appearing in dissipative systems maximize the energy flow through the pattern forming interface.
Staliunas, Kestutis
core +3 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The parametric characteristics of frequency response functions for nonlinear systems [PDF]
, 2006 The characteristics of the frequency response functions of nonlinear systems can be revealed and analyzed through the analysis of the parametric characteristics of these functions.
Billings, S.A. +3 more
core
Stability of Compacton Solutions of Fifth-Order Nonlinear Dispersive Equations
, 2000 We consider fifth-order nonlinear dispersive $K(m,n,p)$ type equations to study the effect of nonlinear dispersion. Using simple scaling arguments we show, how, instead of the conventional solitary waves like solitons, the interaction of the nonlinear ...
Avinash Khare +3 more
core +1 more source
Numerical analysis of nonlinear subdiffusion equations [PDF]
, 2017 We present a general framework for the rigorous numerical analysis of time-fractional nonlinear parabolic partial differential equations, with a fractional derivative of order $\alpha\in(0,1)$ in time.
Jin, Bangti, Li, Buyang, Zhou, Zhi
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Discussion on “Multidimensional Coincidence Points” via Recent Publications
Abstract and Applied Analysis, 2014 We show that some definitions of multidimensional coincidence points are not compatible with the mixed monotone property. Thus, some theorems reported in the recent publications (Dalal et al., 2014 and Imdad et al., 2013) have gaps. We clarify these gaps
Saleh A. Al-Mezel +3 more
doaj +1 more source
Linearized analysis versus optimization-based nonlinear analysis for nonlinear systems [PDF]
, 2009 For autonomous nonlinear systems stability and input-output properties in small enough (infinitesimally small) neighborhoods of (linearly) asymptotically stable equilibrium points can be inferred from the properties of the linearized dynamics.
Packard, Andrew, Topcu, Ufuk
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source