Results 61 to 70 of about 3,102,564 (352)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Wave Energy Dissipation of Spilling and Plunging Breaking Waves in Spectral Models

Journal of Marine Science and Engineering, 2022
On the basis of field experiments and modeling, the dependence of the dissipation of the energy of waves breaking by plunging and spilling on the frequency of wave spectra was investigated. It was shown that the modeling of wave breaking should take into
Yana Saprykina, Burak Aydogan, Berna Ayat   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A fourth-order Runge-Kutta in the interaction picture method for coupled nonlinear Schrodinger equation

, 2010
A fourth-order Runge-Kutta in the interaction picture (RK4IP) method is presented for solving the coupled nonlinear Schrodinger equation (CNLSE) that governs the light propagation in optical fibers with randomly varying birefringence.
Ablowitz, Alperovich, Bosco, Carena, Cartaxo, Chow, Ciaramella, Evangelides, Forestieri, Ghafouri-Shiraz, Hult, Karlsson, Liang Chen, Marcuse, Matera, Menyuk, Menyuk, Secondini, Sinkin, Vannucci, Wai, Wang, Weiss, Xiaoyi Bao, Xie, Zhongxi Zhang   +25 more
core   +1 more source

Piecewise-linear and bilinear approaches to nonlinear differential equations approximation problem of computational structural mechanics

MATEC Web of Conferences, 2017
This paper presents a bilinear approach to nonlinear differential equations system approximation problem. Sometimes the nonlinear differential equations right-hand sides linearization is extremely difficult or even impossible.
Leibov Roman
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

NARX Deep Convolutional Fuzzy System for Modelling Nonlinear Dynamic Processes

Mathematics, 2023
This paper presents a new approach for modelling nonlinear dynamic processes (NDP). It is based on a nonlinear autoregressive with exogenous (NARX) inputs model structure and a deep convolutional fuzzy system (DCFS).
Marjan Golob
doaj   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

The cell-average based neural network for numerical approximation of the nonlinear Schrödinger equation [PDF]

, 2023
Dielan Hu, Changxin Qiu, Bo Yang, Biao Li   +3 more
openalex   +1 more source