Results 61 to 70 of about 2,924,633 (320)

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Piecewise continuous approach to nonlinear differential equations approximation problem of computational structural mechanics

MATEC Web of Conferences, 2018
This paper presents a nonlinear differential equations system piecewise continuous approximation. The piecewise continuous approximation improves piecewise linear approximation through reducing the errors at the boundaries of different linear ...
Leibov Roman
doaj   +1 more source

Homogeneous Approximation of One- Dimensional Series of Iterated Integrals and Time Optimality

Journal of Optimization, Differential Equations and Their Applications, 2023
In the paper we consider nonlinear systems depending linearly on control with one-dimensional output. As is well known, under the analyticity requirement, the output can be expressed as a series of iterated integrals of controls with scalar coefficients.
Daria M. Andreieva, Svetlana Yu. Ignatovich   +1 more
doaj   +1 more source

Nonlinear optimization and approximation

Journal of Approximation Theory, 1973
AbstractThis paper is concerned with nonlinear optimization problems in normed linear spaces. Necessary and sufficient conditions for optimal points are given and the range of applicability of these conditions is studied.The results are applied to nonlinear approximation problems.
openaire   +2 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

A posteriori error estimates of spectral method for nonlinear parabolic optimal control problem

Journal of Inequalities and Applications, 2018
In this paper, we investigate the spectral approximation of optimal control problem governed by nonlinear parabolic equations. A spectral approximation scheme for the nonlinear parabolic optimal control problem is presented. We construct a fully discrete
Lin Li, Zuliang Lu, Wei Zhang, Fei Huang, Yin Yang   +4 more
doaj   +1 more source

Wave Energy Dissipation of Spilling and Plunging Breaking Waves in Spectral Models

Journal of Marine Science and Engineering, 2022
On the basis of field experiments and modeling, the dependence of the dissipation of the energy of waves breaking by plunging and spilling on the frequency of wave spectra was investigated. It was shown that the modeling of wave breaking should take into
Yana Saprykina, Burak Aydogan, Berna Ayat   +2 more
doaj   +1 more source

Mode coupling in the nonlinear response of black holes [PDF]

, 2003
We study the properties of the outgoing gravitational wave produced when a non-spinning black hole is excited by an ingoing gravitational wave. Simulations using a numerical code for solving Einstein's equations allow the study to be extended from the ...
C. Cutler, D. Shoemaker, E. Newman, E.E. Flanagan, H. Bondi, H.-J. Yo, H.-P. Nollert, J. Baker, J. Baker, J. Pullin, Jeffrey Winicour, L. Blanchet, L. Lehner, L. Lehner, Luis Lehner, M. Alcubierre, M. Campanelli, M.A. Scheel, N.T. Bishop, N.T. Bishop, P. Papadopoulos, P.R. Brady, R. Gomez, R. Gomez, R. Gómez, R. Gómez, R. Sachs, Roberto Gómez, S. Husa, S.A. Hughes, S.A. Teukolsky, S.A. Teukolsky, Sascha Husa, T. Damour, T.W. Baumgarte, Yosef Zlochower   +35 more
core   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The Theory and Applications of Hölder Widths

Axioms
We introduce the Hölder width, which measures the best error performance of some recent nonlinear approximation methods, such as deep neural network approximation. Then, we investigate the relationship between Hölder widths and other widths, showing that
Man Lu, Peixin Ye
doaj   +1 more source