Results 41 to 50 of about 61,566 (312)

Multiple solutions for semilinear elliptic equations with nonlinear boundary conditions

Electronic Journal of Differential Equations, 2012
We consider the elliptic problem with nonlinear boundary conditions: $$displaylines{ -Delta u +bu=f(x,u)quadhbox{in }Omega,cr -partial_{u}u=|u|^{q-1}u-g(u)quadhbox{on }partialOmega, }$$ where $Omega$ is a bounded domain in $mathbb{R}^n$.
Junichi Harada, Mitsuharu Otani
doaj  

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Nonlinear Schrodinger equations on the half-line with nonlinear boundary conditions

Electronic Journal of Differential Equations, 2016
In this article, we study the initial boundary value problem for nonlinear Schrodinger equations on the half-line with nonlinear boundary conditions $$ u_x(0,t)+\lambda|u(0,t)|^ru(0,t)=0,\quad \lambda\in\mathbb{R}-\{0\},\; r> 0.
Ahmet Batal, Turker Ozsari
doaj  

Akbari–Ganji Method for Solving Equations of Euler–Bernoulli Beam with Quintic Nonlinearity

Acoustics, 2021
In many real word applications, beam has nonlinear transversely vibrations. Solving nonlinear beam systems is complicated because of the high dependency of the system variables and boundary conditions.
Iman Khatami, Mohsen Zahedi, Abolfazl Zahedi, Mohammad Yaghoub Abdollahzadeh Jamalabadi   +3 more
doaj   +1 more source

Ulam–Hyers Stability and Uniqueness for Nonlinear Sequential Fractional Differential Equations Involving Integral Boundary Conditions [PDF]

, 2021
Areen Al-Khateeb, Hamzeh Zureigat, Osama Ala’yed, Sameer Bawaneh   +3 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Nonlinear Cylindrical Markers Using Metamaterials

Remote Sensing, 2021
In this paper, the research of nonlinear cylindrical metastructure was obtained. An algorithm for finding the total field of a nonlinearly loaded perfectly conducting cylinder covered with a metamaterial (MM) layer based on Maxwell’s equations with ...
Diana V. Semenikhina, Nikolay N. Gorbatenko   +1 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source