Results 41 to 50 of about 65,332 (306)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Multiple solutions for fractional differential equations with nonlinear boundary conditions
In this paper, we study certain fractional differential equations with nonlinear boundary conditions. By means of the Amann theorem and the method of upper and lower solutions, some new results on the multiple solutions are ...
Liu, Xiping, Jia, Mei
core +1 more source
On delay differential equations with nonlinear boundary conditions
The monotone iterative method is used to obtain sufficient conditions which guarantee that a delay differential equation with a nonlinear boundary condition has quasisolutions, extremal solutions, or a unique solution.
Jankowski Tadeusz
doaj +2 more sources
The paper examines a system of nonlinear integro-differential equations with three-point and nonlinear integral boundary conditions. The original problem demonstrated to be equivalent to integral equations by using Green function.
M.J. Mardanov +2 more
doaj +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
Fourth-order problems with fully nonlinear boundary conditions
Differential inequality method, bounding function method and topological degree are applied to obtain the existence criterions of at least one solution for the general fourth-order differential equations under nonlinear boundary conditions, and many ...
Wang, Guangwa, Sun, Li, Zhou, Mingru
core +1 more source
Fully nonlinear boundary value problems with impulse
An impulsive boundary value problem with nonlinear boundary conditions for a second order ordinary differential equation is studied. In particular, sufficient conditions are provided so that a compression - expansion cone theoretic fixed point theorem ...
Paul Eloe, M. Usman
doaj +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
Multiple solutions for semilinear elliptic equations with nonlinear boundary conditions
We consider the elliptic problem with nonlinear boundary conditions: $$displaylines{ -Delta u +bu=f(x,u)quadhbox{in }Omega,cr -partial_{u}u=|u|^{q-1}u-g(u)quadhbox{on }partialOmega, }$$ where $Omega$ is a bounded domain in $mathbb{R}^n$.
Junichi Harada, Mitsuharu Otani
doaj
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir +2 more
wiley +1 more source

