Results 41 to 50 of about 65,332 (306)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Multiple solutions for fractional differential equations with nonlinear boundary conditions

open access: yes, 2010
In this paper, we study certain fractional differential equations with nonlinear boundary conditions. By means of the Amann theorem and the method of upper and lower solutions, some new results on the multiple solutions are ...
Liu, Xiping, Jia, Mei
core   +1 more source

On delay differential equations with nonlinear boundary conditions

open access: yesBoundary Value Problems, 2005
The monotone iterative method is used to obtain sufficient conditions which guarantee that a delay differential equation with a nonlinear boundary condition has quasisolutions, extremal solutions, or a unique solution.
Jankowski Tadeusz
doaj   +2 more sources

Existence and uniqueness of solutions for the system of integro-differential equations with three-point and nonlinear integral boundary conditions

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2020
The paper examines a system of nonlinear integro-differential equations with three-point and nonlinear integral boundary conditions. The original problem demonstrated to be equivalent to integral equations by using Green function.
M.J. Mardanov   +2 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Fourth-order problems with fully nonlinear boundary conditions

open access: yes, 2007
Differential inequality method, bounding function method and topological degree are applied to obtain the existence criterions of at least one solution for the general fourth-order differential equations under nonlinear boundary conditions, and many ...
Wang, Guangwa, Sun, Li, Zhou, Mingru
core   +1 more source

Fully nonlinear boundary value problems with impulse

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2011
An impulsive boundary value problem with nonlinear boundary conditions for a second order ordinary differential equation is studied. In particular, sufficient conditions are provided so that a compression - expansion cone theoretic fixed point theorem ...
Paul Eloe, M. Usman
doaj   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

Multiple solutions for semilinear elliptic equations with nonlinear boundary conditions

open access: yesElectronic Journal of Differential Equations, 2012
We consider the elliptic problem with nonlinear boundary conditions: $$displaylines{ -Delta u +bu=f(x,u)quadhbox{in }Omega,cr -partial_{u}u=|u|^{q-1}u-g(u)quadhbox{on }partialOmega, }$$ where $Omega$ is a bounded domain in $mathbb{R}^n$.
Junichi Harada, Mitsuharu Otani
doaj  

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir   +2 more
wiley   +1 more source

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