Results 21 to 30 of about 57,739 (263)

The double auxiliary equations method and its application to space-time fractional nonlinear equations

open access: yesJournal of Ocean Engineering and Science, 2019
This paper reflects the execution of a reliable technique which we proposed as a new method called the double auxiliary equations method for constructing new traveling wave solutions of nonlinear fractional differential equation.
L.A. Alhakim, A.A. Moussa
doaj   +1 more source

The Combined RKM and ADM for Solving Nonlinear Weakly Singular Volterra Integrodifferential Equations

open access: yesAbstract and Applied Analysis, 2012
The reproducing kernel method (RKM) and the Adomian decomposition method (ADM) are applied to solve nth-order nonlinear weakly singular Volterra integrodifferential equations. The numerical solutions of this class of equations have been a difficult topic
Xueqin Lv, Sixing Shi
doaj   +1 more source

Nonlinear differential equation with first order partial derivatives

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2018
The asymptotic behavior of solutions of a nonlinear differential equation with first-order partial derivatives solved with respect to one of the derivatives is investigated.
T. М. Aldibekov, M. M. Aldazharova
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

New solutions to a category of nonlinear PDEs

open access: yesFrontiers in Physics
The nonlinear partial differential equations are not only used in many physical models, but also fundamentally applied in the field of nonlinear science. In order to solve certain nonlinear partial differential equation, the extended hyperbolic auxiliary
Bacui Li, Fuzhang Wang
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Application of decomposition to hyperbolic, parabolic, and elliptic partial differential equations

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1989
The decomposition method is applied to examples of hyperbolic, parabolic, and elliptic partial differential equations without use of linearizatlon techniques.
G. Adomian
doaj   +1 more source

Exact solutions of some nonlinear evolution equations via the first integral method

open access: yesAin Shams Engineering Journal, 2013
The first integral method can be used to construct exact traveling wave solutions of nonlinear partial differential equations. In this work, we explore new application of this method to some special nonlinear partial differential equations.
N. Taghizadeh   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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