Results 41 to 50 of about 398,053 (318)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
New Journal of Physics, 2017 The quasi-coherent effects in two-dimensional incompressible turbulence are analyzed starting from the test particle trajectories. They can acquire coherent aspects when the stochastic potential has slow time variation and the motion is not strongly ...
M Vlad, F Spineanu
doaj +1 more source
Compact Optical Switches and Modulators Based on Dispersion Engineered Photonic Crystals
IEEE Photonics Journal, 2010 We use slow-light photonic crystals to enhance optical switching and modulation in silicon. By using dispersion-engineered designs, a switch as short as 5 ¿m was achieved, in which we have demonstrated rerouting of optical pulses on a 3-ps time scale ...
Liam O'Faolain +5 more
doaj +1 more source
Investigating the effects of introducing nonlinear dynamical processes into digital musical interfaces [PDF]
, 2015 This paper presents the results of a study that explores the effects of including nonlinear dynamical processes in the design of digital musical interfaces.
Paul Mulholland +8 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Characterization of nonlinear switching in a figure-of-eight fiber laser using frequency-resolved optical gating [PDF]
, 1998 The measurement technique of frequency-resolved optical gating is applied to determine the nonlinear switching characteristics of a passively modelocked figure-of-eight erbium-doped fiber laser. By completely characterizing the intensity and phase of the
Barry, Liam P. +4 more
core +1 more source
Nonlinear Optical Effects [PDF]
, 1971 Third-harmonic generation in cholesteric liquid crystals, far-infrared generation by ultrashort pulses, and self-focusing of light in nonlinear media are taken as examples for illustration of nonlinear optical effects. Depending on the problems, different approximations are used in solving the nonlinear wave equations.
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Effective Computation for Nonlinear Systems [PDF]
, 2007 Nonlinear dynamical and control systems are an important source of applications for theories of computation over the the real numbers, since these systems are usually to complicated to study analytically, but may be extremely sensitive to numerical error.
openaire +2 more sources
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source