Results 31 to 40 of about 5,063,540 (351)

Analytical approximate solutions to the nonlinear Fornberg–Whitham type equations via modified variational iteration method

Partial Differential Equations in Applied Mathematics
In this paper, we utilize the modified variational iteration method introduced by Abassy et al. for obtaining the analytical approximate solutions of the nonlinear Fornberg–Whitham equation and modified nonlinear Fornberg–Whitham equation.
Md. Asaduzzaman, Faruk Özger, Adem Kilicman   +2 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Efficient two-step with memory methods and their dynamics. [PDF]

Mathematics and Computational Sciences
In this work,a fourth-order without-memory method is proposed that has a self-accelerator parameter.This method doesn’t need to compute a derivative function forsolving nonlinear equations.We have approximated the self-accelerator parameter andhave ...
Vali Torkashvand
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Novel soliton solutions and phase plane analysis in nonlinear Schrödinger equations with logarithmic nonlinearities

Scientific Reports
This paper investigates a generalized form of the nonlinear Schrödinger equation characterized by a logarithmic nonlinearity. The nonlinear Schrödinger equation, a fundamental equation in nonlinear wave theory, is applied across various physical systems ...
Du’a Al-zaleq, Lewa’ Alzaleq
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

An Analysis of the Nonstandard Finite Difference and Galerkin Methods Applied to the Huxley Equation

Mathematics
The Huxley equation, which is a nonlinear partial differential equation, is used to describe the ionic mechanisms underlying the initiation and propagation of action potentials in the squid giant axon.
Pius W. M. Chin, Claude R. B. Moutsinga, Khadijo R. Adem   +2 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Parabolic equation with exponential nonlinearity as the condition of joint venture linear system

Наука. Инновации. Технологии, 2022
An attempt is made to construct a 2 + 1 - dimensional nonlinear model that is a condition for the compatibility of a system of two first - order linear differential equations. The resulting equation is related to the operator L, A to the pair and the Lax
Olesya Borisovna Surneva, Olga Sergeevna Yanovskaya   +1 more
doaj