Results 41 to 50 of about 1,142,971 (318)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
On discrete analogues of nonlinear implicit differential equations
Advances in Difference Equations, 2006 This paper deals with some classes of nonlinear implicit difference equations obtained via discretization of nonlinear differential-algebraic or partial differential-algebraic equations.
Anh Pham Ky, Loi Le Cong
doaj +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Practical Ulam-Hyers-Rassias stability for nonlinear equations [PDF]
Mathematica Bohemica, 2017 In this paper, we offer a new stability concept, practical Ulam-Hyers-Rassias stability, for nonlinear equations in Banach spaces, which consists in a restriction of Ulam-Hyers-Rassias stability to bounded subsets.
Jin Rong Wang, Michal Fečkan
doaj +1 more source
Multidimensional transonic shock waves and free boundary problems
Bulletin of Mathematical Sciences, 2022 We are concerned with free boundary problems arising from the analysis of multidimensional transonic shock waves for the Euler equations in compressible fluid dynamics.
Gui-Qiang G. Chen, Mikhail Feldman
doaj +1 more source
Current Interactions from the One-Form Sector of Nonlinear Higher-Spin Equations
, 2018 The form of higher-spin current interactions in the sector of one-forms is derived from the nonlinear higher-spin equations in $AdS_4$. Quadratic corrections to higher-spin equations are shown to be independent of the phase of the parameter $\eta =\exp i\
Gelfond, O. A., Vasiliev, M. A.
core +2 more sources
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Improved ()-Expansion Method for the Space and Time Fractional Foam Drainage and KdV Equations
Abstract and Applied Analysis, 2013 The fractional complex transformation is used to transform nonlinear partial differential equations to nonlinear ordinary differential equations. The improved ()-expansion method is suggested to solve the space and time fractional foam drainage and KdV ...
Ali Akgül +2 more
doaj +1 more source
Nonlinear self-adjointness and conservation laws
, 2011 The general concept of nonlinear self-adjointness of differential equations is introduced. It includes the linear self-adjointness as a particular case.
Dorodnitsyn V A +12 more
core +1 more source