Results 31 to 40 of about 18,172 (251)
Applied Sciences, 2020 Friction-Induced Vibration and noisE (FIVE) is still a complex and nonlinear physical phenomenon which is characterized by the appearance of instabilities and self-sustained vibrations.
Baptiste Chomette, Jean-Jacques Sinou
doaj +1 more source
Design and Evaluation of a Balanced Compliant Laparoscopic Grasper
IEEE Journal of Translational Engineering in Health and Medicine, 2023 In laparoscopic surgery, quality of haptic feedback is reduced compared to conventional surgery, leading to unintentional tissue damage during grasping.
Jan-Willem Klok +4 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Identification of Nonlinear Feedback Mechanisms Operating in Closed Loop using Inertial Sensors
IFAC-PapersOnLine, 2018 In this paper we study the problem of identifying linear and nonlinear feedback mechanisms, or controllers, operating in closed loop.
Olsson, Fredrik +3 more
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Nonlinear Dynamics, 2022 Abstract Self-excited periodic, quasiperiodic and chaotic oscillations have many significant applications in engineering devices and processes. In the present paper a centralized nonlinear controller is proposed to artificially generate and control self-excited periodic, quasiperiodic, chaotic and hyper-chaotic oscillations of required ...
Prasanjit Kumar Kundu +1 more
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Journal of Applied Mathematics, 2013 The structural scheme of mechanical elastic energy storage (MEES) system served by permanent magnet synchronous motor (PMSM) and bidirectional converters is designed.
Yang Yu, Zengqiang Mi
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Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu +7 more
wiley +1 more source
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source