Results 41 to 50 of about 12,217,658 (292)

Discrete Mechanics and Optimal Control for Space Trajectory Design [PDF]

open access: yes, 2011
Space trajectory design is often achieved through a combination of dynamical systems theory and optimal control. The union of trajectory design techniques utilizing invariant manifolds of the planar circular restricted three-body problem and the optimal ...
Moore, Ashley
core   +1 more source

Coupled 6DoF nonlinear model of tactical missiles: an optimal autopilot design [PDF]

open access: yesArchives of Control Sciences
A fully coupled six degrees of freedom modelling of a tactical missile and an optimal control theory-based method are presented aiming at minimizing the autopilot control effort and improving the accuracy of reaching the target by a missile guidance ...
Tadeusz Mikutel   +2 more
doaj   +1 more source

Mathematical Modelling and Optimal Control of Anthracnose

open access: yesBiomath, 2014
In this paper we propose two nonlinear models for the control of anthracnose disease. The first one is an ordinary differential equation (ODE) model which represents the whithin host evolution of the disease.
David Fotsa   +4 more
doaj   +1 more source

Optimal Control Problems for Nonlinear Variational Evolution Inequalities

open access: yesAbstract and Applied Analysis, 2013
We deal with optimal control problems governed by semilinear parabolic type equations and in particular described by variational inequalities. We will also characterize the optimal controls by giving necessary conditions for optimality by proving the ...
Eun-Young Ju, Jin-Mun Jeong
doaj   +1 more source

An Improved Nonlinear Predictive Control Strategy Enhanced by Fractional Order Extremum Seeking Control of the Antilock Braking System of a Vehicle

open access: yesIEEE Access, 2020
Extremum seeking control can search the optimal slip rate of the antilock braking system of a vehicle through a high-frequency sinusoidal excitation signal.
Ren He, Lei Yuan
doaj   +1 more source

A multilevel approach for stochastic nonlinear optimal control [PDF]

open access: yesInternational Journal of Control, 2020
We consider a class of finite time horizon nonlinear stochastic optimal control problem, where the control acts additively on the dynamics and the control cost is quadratic. This framework is flexible and has found applications in many domains. Although the optimal control admits a path integral representation for this class of control problems ...
Ajay Jasra   +3 more
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Online-Computation Approach to Optimal Control of Noise-Affected Nonlinear Systems with Continuous State and Control Spaces [PDF]

open access: yes, 2007
22.10.13 KB. Ok to add author version to spiral.A novel online-computation approach to optimal control of nonlinear, noise-affected systems with continuous state and control spaces is presented.
Deisenroth, Marc P   +3 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Optimal control of nonlinear systems with input constraints using linear time varying approximations [PDF]

open access: yes, 2016
We propose a new method to solve input constrained optimal control problems for autonomous nonlinear systems affine in control. We then extend the method to compute the bang-bang control solutions under the symmetric control constraints.
Itik, Mehmet
core   +1 more source

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