Results 91 to 100 of about 458,466 (259)

Integrated Population Pharmacokinetic, Pharmacodynamic, and Safety Analyses to Inform Dosage Selection in the Clinical Development of the ATR Inhibitor Tuvusertib

Clinical Pharmacology &Therapeutics, EarlyView.
We present model‐informed selection of the recommended dose for expansion (RDE) of investigational oral ATR inhibitor tuvusertib, by integrating clinical pharmacokinetics (PK), pharmacodynamics (PD), and safety data from DDRiver Solid Tumors 301 trial Part A1 (NCT04170153).
Jatinder Kaur Mukker, Paul Matthias Diderichsen, Farina Hellmann, Timothy A. Yap, Ruth Plummer, Anthony W. Tolcher, Johann S. de Bono, Ioannis Gounaris, Zoltan Szucs, Astrid Zimmermann, Irina Kareva, Jayaprakasam Bolleddula, Annick Seithel‐Keuth, Giuseppe Locatelli, Marta Enderlin, Christine Hicking, Anup Zutshi, Wei Gao, Rainer Strotmann, Lisa Benincosa, Karthik Venkatakrishnan   +20 more
wiley   +1 more source

PERIODIC STATES NEAR THE PLANE DEFECT WITH NON-LINEAR RESPONSE SEPARATING NON-LINEAR SELF-FOCUSING AND LINEAR CRYSTALS

Конденсированные среды и межфазные границы, 2018
The paper presents a model describing the peculiarities of localised excitation on the boundary between linear and nonlinear self-focusing media. The medium boundary is a plane defect with internal nonlinear properties.
Sergey E. Savotchenko
doaj   +1 more source

Suprathermal Soliton Solutions to Nonlinear Schrödinger Equation

Contributions to Plasma Physics, EarlyView.
ABSTRACT Maxwell distributions are very difficult to find in the low‐pressure environment far away the Earth atmosphere, permeated by high temperatures, various types of radiation, highly energetic particles, space debris, and subjected to microgravity, presenting crucial challenges for spacecraft design and operations, and affecting astronaut's health.
F. E. M. Silveira, M. H. Benetti, I. L. Caldas   +2 more
wiley   +1 more source

Long time stability of KAM tori for the nonlinear Schrödinger equation [PDF]

, 2021
Xiaolong He, Jia Shi, Xiaoping Yuan
openalex   +1 more source

Birkhoff Coordinates for the Focusing NLS Equation [PDF]

, 2018
In this paper we construct Birkhoff coordinates for the focusing nonlinear Schrödinger equation near the zero ...
Kappeler, T., Lohrmann, P., Topalov, P., Zung, N.   +3 more
core  

Generalized Chemical Model for Warm Dense Hydrogen: Ionization Potential Depression and Molecular Dissociation Shifts

Contributions to Plasma Physics, EarlyView.
ABSTRACT Warm dense matter (WDM) is a complex state, where quantum effects, thermal excitations, and strong interparticle correlations coexist. Understanding its microscopic composition and medium‐induced modifications of atomic and molecular properties is essential for planetary modeling, fusion research, and high‐energy‐density experiments.
L. T. Yerimbetova, Yu. V. Arkhipov, Ye. S. Mukhametkarimov, A. E. Davletov, I. M. Tkachenko   +4 more
wiley   +1 more source

Nonlinear Schrödinger type tetrahedron maps

Nuclear Physics B, 2020
This paper is concerned with the construction of new solutions in terms of birational maps to the functional tetrahedron equation and parametric tetrahedron equation.
S. Konstantinou-Rizos
doaj   +1 more source

TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data

Cytometry Part A, EarlyView.
TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou, Thomas Matthes, Stéphane Marchand‐Maillet   +2 more
wiley   +1 more source

Inverse scattering transform for the nonlocal nonlinear Schrödinger equation with nonzero boundary conditions [PDF]

, 2016
In 2013, a new nonlocal symmetry reduction of the well-known AKNS (an integrable system of partial differential equations, introduced by and named after Mark J. Ablowitz, David J. Kaup, and Alan C. Newell et al. (1974)) scattering problem was found.
M. Ablowitz, Xu‐Dan Luo, Z. Musslimani
semanticscholar   +1 more source

Advances in Position‐Momentum Entanglement: A Versatile Tool for Quantum Technologies

Laser &Photonics Reviews, EarlyView.
Position–momentum entanglement constitutes a high‐dimensional continuous‐variable resource in quantum optics. Recent advances in its generation, characterization, and control are reviewed, with emphasis on spontaneous parametric down‐conversion and modern measurement techniques.
Satyajeet Patil, Rajshree Swarnkar, Jonas L. Moos, Sebastian Töpfer, Sergio Tovar‐Pérez, Jorge Fuenzalida, Markus Gräfe   +6 more
wiley   +1 more source