Results 71 to 80 of about 785,707 (321)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Stability criteria for nonlinear Volterra integro-dynamic matrix Sylvester systems on measure chains

open access: yesAdvances in Difference Equations, 2021
In this paper, we establish sufficient conditions for various stability aspects of a nonlinear Volterra integro-dynamic matrix Sylvester system on time scales.
Sreenivasulu Ayyalappagari   +1 more
doaj   +1 more source

Nonlinearity and disorder:  Classification and stability of nonlinear impurity modes [PDF]

open access: yesPhysical Review E, 2001
18 pages, 22 ...
Bang, Ole   +4 more
openaire   +4 more sources

Global and Regional Temporal Changes in Cross‐Country Inequalities of Site‐Specific Osteoarthritis Burden, 1990 to 2021

open access: yesArthritis Care &Research, EarlyView.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rates (ASYRs) for site‐specific OA across 204 countries and territories were obtained from the Global Burden of Diseases, Injuries, and ...
Haowei Chen   +14 more
wiley   +1 more source

Stability of Nonlinear AR-GARCH Models [PDF]

open access: yesSSRN Electronic Journal, 2006
Abstract.  This article studies the stability of nonlinear autoregressive models with conditionally heteroskedastic errors. We consider a nonlinear autoregression of order p [AR(p)] with the conditional variance specified as a nonlinear first‐order generalized autoregressive conditional heteroskedasticity [GARCH(1,1)] model.
MEITZ, Mika, SAIKKONEN, Pentti
openaire   +8 more sources

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer   +5 more
wiley   +1 more source

Nonlinear Stability of Eady's Model [PDF]

open access: yesJournal of the Atmospheric Sciences, 1994
A nonlinear stability theorem is established for Eady's model of baroclinic flow. In particular, the Eady basic state is shown to be nonlinearly stable (for arbitrary shear) provided (Δz)/(Δy) > 2(5)^1/2f/(πN),where Δz is the height of the domain, Δy the channel width, f the Coriolis parameter, and N the buoyancy frequency.
Mu, Mu, Shepherd, Theodore G.
openaire   +2 more sources

Nonlinear modes in finite-dimensional PT-symmetric systems

open access: yes, 2012
By rearrangements of waveguide arrays with gain and losses one can simulate transformations among parity-time (PT-) symmetric systems not affecting their pure real linear spectra.
Konotop, V. V., Zezyulin, D. A.
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

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