Results 71 to 80 of about 4,997,800 (374)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Stable self-similar blowup in energy supercritical Yang-Mills theory
, 2012 We consider the Cauchy problem for an energy supercritical nonlinear wave equation that arises in $(1+5)$--dimensional Yang--Mills theory. A certain self--similar solution $W_0$ of this model is conjectured to act as an attractor for generic large data ...
Donninger, Roland
core +1 more source
Stability criteria for nonlinear Volterra integro-dynamic matrix Sylvester systems on measure chains
Advances in Difference Equations, 2021 In this paper, we establish sufficient conditions for various stability aspects of a nonlinear Volterra integro-dynamic matrix Sylvester system on time scales.
Sreenivasulu Ayyalappagari +1 more
doaj +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
A non-variational approach to nonlinear stability in stellar dynamics applied to the King model
, 2006 In previous work by Y. Guo and G. Rein, nonlinear stability of equilibria in stellar dynamics, i.e., of steady states of the Vlasov-Poisson system, was accessed by variational techniques.
A. Burchard +26 more
core +1 more source
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Nonlinear modes in finite-dimensional PT-symmetric systems
, 2012 By rearrangements of waveguide arrays with gain and losses one can simulate transformations among parity-time (PT-) symmetric systems not affecting their pure real linear spectra.
Konotop, V. V., Zezyulin, D. A.
core +1 more source
Energies, 2022 This paper investigates the nonlinear modeling and stability of a doubly-fed variable speed pumped storage power station (DFVSPSPS). Firstly, the mathematical model of DFVSPSPS with surge tank considering nonlinear pump turbine characteristics was ...
Nan Zhang +5 more
doaj +1 more source
Nonlinear stability of cosmological solutions in massive gravity [PDF]
, 2013 We investigate nonlinear stability of two classes of cosmological solutions in massive gravity: isotropic Friedmann-Lemaitre-Robertson-Walker (FLRW) solutions and anisotropic FLRW solutions.
A. D. Felice +3 more
semanticscholar +1 more source
Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase
FEBS Open Bio, EarlyView.The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni +4 more
wiley +1 more source