Results 51 to 60 of about 5,427,805 (312)

Nonlinear stability of the ensemble Kalman filter with adaptive covariance inflation [PDF]

open access: yes, 2015
The Ensemble Kalman filter and Ensemble square root filters are data assimilation methods used to combine high dimensional nonlinear models with observed data.
Xin T. Tong, A. Majda, David Kelly
semanticscholar   +1 more source

Thermal Convection in a Rotating Anisotropic Fluid Saturated Darcy Porous Medium

open access: yesFluids, 2017
The stability of the thermal convection in a fluid-saturated rotating anisotropic porous material is investigated. We take into account the rotation of a layer of saturated porous medium about an axis orthogonal to the planes bounding the layer.
Shatha Haddad
doaj   +1 more source

Nonlinear stability in nonlocal gravity [PDF]

open access: yesPhysical Review D, 2019
We address the stability issue of Ricci-flat and maximally symmetric spacetimes in nonlocal gravity to all perturbative orders in the gravitational perturbation. Assuming a potential at least cubic in curvature tensors but quadratic in the Ricci tensor, our proof consists on a mapping of the stability analysis in nonlocal gravity to the same problem in
Briscese, Fabio   +2 more
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Stability and Analytic Solutions of an Optimal Control Problem on the Schrödinger Lie Group

open access: yesOpen Physics, 2016
The nonlinear stability and the existence of the periodic solutions for an optimal control problem on the Schrödinger Lie group are discussed. The analytic solutions via optimal homotopy asymptotic method of the dynamics and numerical simulations are ...
Ene Remus-Daniel   +2 more
doaj   +1 more source

Systematic Review of Geometrical Approaches and Analytical Integration for Chen’s System

open access: yesMathematics, 2020
The main goal of this paper is to present an analytical integration in connection with the geometrical frame given by the Hamilton–Poisson formulation of a specific case of Chen’s system. In this special case we construct an analytic approximate solution
Remus-Daniel Ene   +2 more
doaj   +1 more source

Discovering governing equations from data by sparse identification of nonlinear dynamical systems [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Significance Understanding dynamic constraints and balances in nature has facilitated rapid development of knowledge and enabled technology, including aircraft, combustion engines, satellites, and electrical power. This work develops a novel framework to
S. Brunton, J. L. Proctor, J. Kutz
semanticscholar   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Thermodynamics and Stability of Non-Equilibrium Steady States in Open Systems

open access: yesEntropy, 2019
Thermodynamical arguments are known to be useful in the construction of physically motivated Lyapunov functionals for nonlinear stability analysis of spatially homogeneous equilibrium states in thermodynamically isolated systems.
Miroslav Bulíček   +2 more
doaj   +1 more source

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