Results 51 to 60 of about 216,988 (317)
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Stability problems and numerical integration on the Lie group SO(3) × R3 × R3
Open Mathematics, 2018 The paper is dealing with stability problems for a nonlinear system on the Lie group SO(3) × R3 × R3. The approximate analytic solutions of the considered system via Optimal Homotopy Asymptotic Method are presented, too.
Pop Camelia, Ene Remus-Daniel
doaj +1 more source
, 2017 In this paper, deterministic and stochastic SEIRI epidemic models featuring a distributed latent period and general, unspecified nonlinear incidence and growth rates for the susceptible class are proposed and investigated from a stability viewpoint.
Xia, Juan, Zhang, Hong, Georgescu, Paul
core +1 more source
Input-to-state stability for discrete-time time-varying systems with applications to robust stabilization of systems in power form [PDF]
, 2005 Input-to-state stability (ISS) of a parameterized family of discrete-time time-varying nonlinear systems is investigated. A converse Lyapunov theorem for such systems is developed.
Laila, D. S. +5 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Nonlinear stability in nonlocal gravity [PDF]
Physical Review D, 2019 We address the stability issue of Ricci-flat and maximally symmetric spacetimes in nonlocal gravity to all perturbative orders in the gravitational perturbation. Assuming a potential at least cubic in curvature tensors but quadratic in the Ricci tensor, our proof consists on a mapping of the stability analysis in nonlocal gravity to the same problem in
Briscese, Fabio +2 more
openaire +4 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Demonstratio MathematicaIn this article, we study the inviscid limit of the solution to the Cauchy problem of a one-dimensional viscous conservation law, where the second-order term is nonlinear. Under the assumption that the inviscid equation admits a piecewise smooth solution
Feng Li, Wang Jing
doaj +1 more source
, 2022 This research work is dedicated to an investigation for a new kind of boundary value problem of nonlinear fractional differential equation supplemented with general boundary condition.
Liu, Weiwei, Liu, Lishan
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Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source