Results 61 to 70 of about 24,564,249 (381)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Finite-dimensional states and entanglement generation for a nonlinear coupler
, 2006 We discuss a system comprising two nonlinear (Kerr-like) oscillators coupled mutually by a nonlinear interaction. The system is excited by an external coherent field that is resonant to the frequency of one of the oscillators.
A. Chefles +10 more
core +1 more source
Controllability distributions and systems approximations: a geometric approach [PDF]
, 1994 Given a nonlinear system we determine a relation at an equilibrium between controllability distributions defined for a nonlinear system and a Taylor series approximation of it. The value of such a relation is appreciated if we recall that the solvability
Nijmeijer, H., Ruiz, A.C.
core +3 more sources
Nonlinear Supratransmission in Multicomponent Systems [PDF]
Physical Review Letters, 2010 A method is proposed to solve the challenging problem of determining the supratransmission threshold (onset of instability of harmonic boundary driving inside a band gap) in multicomponent nonintegrable nonlinear systems. It is successfully applied to the degenerate three-wave resonant interaction in a birefringent quadratic medium where the process ...
Anghel-Vasilescu, Petrutza +4 more
openaire +5 more sources
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
IEEE Access, 2019 This paper develops a new adaptive control scheme for a class of incommensurate fractional order nonlinear systems with external disturbances and input dead-zone.
Changhui Wang, Mei Liang, Yongsheng Chai
doaj +1 more source
Nonlinear normal modes, modal interactions and isolated resonance curves [PDF]
, 2015 The objective of the present study is to explore the connection between the nonlinear normal modes of an undamped and unforced nonlinear system and the isolated resonance curves that may appear in the damped response of the forced system. To this end, an
Allen, Matthew S. +5 more
core +2 more sources
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Feedback Robust Cubature Kalman Filter for Target Tracking Using an Angle Sensor
Sensors, 2016 The direction of arrival (DOA) tracking problem based on an angle sensor is an important topic in many fields. In this paper, a nonlinear filter named the feedback M-estimation based robust cubature Kalman filter (FMR-CKF) is proposed to deal with ...
Hao Wu +3 more
doaj +1 more source