Results 51 to 60 of about 465,530 (295)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Seismic Performance Evaluation of Multi-Storey Residential Building with Friction Pendulum Bearings: Indonesia case study

Structural Mechanics of Engineering Constructions and Buildings
The methodology for seismic performance evaluation of a residential building in Indonesia with the use of seismic isolation is considered. An 8-storey reinforced concrete frame residential building with shear wall structural system was selected as a case
Zaurbek K. Abaev, Faiz Sulthan
doaj   +1 more source

Seismic Performance Comparison of Simply Supported Hollow Slab on Pile Group Structure with Different Operational Category and Shear Panel Damper Application

Civil Engineering Dimension, 2023
This study is aimed to compare the seismic performance of simply supported hollow slab on pile group (SHSPG) structures designed as “critical” and “essential” viaducts with shear panel damper (SPD) devices.
Yusuf Haroki, Ali Awaludin, Henricus Priyosulistyo, Angga Fajar Setiawan, Iman Satyarno   +4 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

The Neural Particle Filter [PDF]

, 2016
The robust estimation of dynamically changing features, such as the position of prey, is one of the hallmarks of perception. On an abstract, algorithmic level, nonlinear Bayesian filtering, i.e.
Kutschireiter, Anna, Pfister, Jean-Pascal, Sprekeler, Henning, Surace, Simone Carlo   +3 more
core   +6 more sources

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Formation of standing shocks in stellar winds and related astrophysical flows [PDF]

, 1983
Stellar winds and other analogous astrophysical flows can be described, to lowest order, by the familiar one dimensional hydrodynamic equations which, being nonlinear, admit in some instances discontinuous as well as continuous transonic solutions for ...
Habbal, S. R., Rosner, R., Tsinganos, K.
core   +1 more source

Assessment of Tension-Only Concentrically Braced Steel Frames in Relation to Seismic Pounding

Applied Sciences
This research examined the phenomenon of pounding between neighboring steel structures, both with and without tension-only braces, utilizing an extensive nonlinear time-history analysis.
Panagiota S. Katsimpini, George A. Papagiannopoulos, George D. Hatzigeorgiou   +2 more
doaj   +1 more source

Real-Time City-Scale Time-History Analysis and Its Application in Resilience-Oriented Earthquake Emergency Responses

Applied Sciences, 2019
The resilience of cities has received worldwide attention. An accurate and rapid assessment of seismic damage, economic loss, and post-event repair time can provide an important reference for emergency rescue and post-earthquake recovery.
Xinzheng Lu, Qingle Cheng, Zhen Xu, Yongjia Xu, Chujin Sun   +4 more
doaj   +1 more source